Baseline characteristics for ER-LVO and NER-LVO patients.
| Baseline clinical characteristics* | ER-LVO, n=48 | NER-LVO, n=101 | P-value |
| Age – median (IQR) | 74 (59–84) | 76 (63–84) | 0.78 |
| Sex, female – no./ total (%) | 27/48 (56%) | 55/101 (54%) | 0.84 |
| Medical history – no./total (%) | |||
| Previous stroke | 8/48 (17%) | 18/100 (18%) | 0.84 |
| Diabetes mellitus | 7/48 (15%) | 11/100 (11%) | 0.53 |
| Coronary artery disease | 1/48 (2%) | 9/100 (9%) | 0.17 |
| Hypertension | 15/48 (31%) | 49/100 (49%) | 0.04 |
| Atrial fibrillation | 9/48 (19%) | 24/100 (24%) | 0.47 |
| Pre-stroke mRS – no./total (%) | 0.72 | ||
| 0 | 7/19 (37%) | 10/37 (27%) | |
| 1 | 11/19 (58%) | 25/37 (67%) | |
| 2 | 0/19 (0%) | 1/37 (3%) | |
| 3 | 1/19 (5%) | 1/37 (3%) | |
| Systolic blood pressure† (mmHg) – median (IQR) | 147 (134–163) | 150 (126–168) | 0.93 |
| Diastolic blood pressure† (mmHg) – median (IQR) | 83 (72–92) | 82 (71–90) | 0.90 |
| Pulse pressure† (mmHg) median (IQR) | 68 (50–80) | 63 (50–80) | 0.95 |
| NIHSSPSC‡ – median (IQR) | 10 (7–15) | 11 (7–16) | 0.75 |
| NIHSSCSC§ – median (IQR) | 4 (1–9) | 14 (7–19) | <0.01 |
| ΔNIHSS‡ – median (IQR) | −5 (−3-(−9)) | 3 (7-(−3)) | <0.01 |
| IVT – no./total (%) | 42/48 (88%) | 79/101 (78%) | 0.18 |
Number of missing values: †5, ‡9, §2.
*All baseline characteristics were measured on arrival at the CSC, unless reported otherwise.
CSC, comprehensive stroke center; ER-LVO, early-recanalized large vessel occlusion; IVT, intravenous treatment with alteplase; mRS, modified Rankin Scale; NER-LVO, non-early-recanalized large vessel occlusion; NIHSS, National Institutes of Health Stroke Scale; ΔNIHSS, change in NIHSS score between presentation to the PSC and presentation to the CSC; NIHSSCSC, NIHSS on CSC admission; NIHSSPSC, NIHSS on PSC admission; PSC, primary stroke center.