Good functional outcome (mRS ≤1, n=101) | Poor functional outcome (mRS >1, n=138) | P-value | |
Age (years), median (IQR) | 72 (63;81) | 76 (63.25;84) | 0.114 |
Female gender, n (%) | 54 (53.5) | 70 (50.7) | 0.675 |
NIHSS score at admission, median (IQR) | 13(7;19) | 17(12;21) | <0.001 |
ASPECTS at admission, median (IQR) | 10 (8;10) | 8 (7;9) | <0.001 |
Last time seen well (min), median (IQR) | 252 (159.75;491.75) | 289 (167.75;540.25) | 0.578 |
IV tPA administered, n (%) | 0.575 | ||
None | 70 (69.3) | 104 (75.4) | |
Partial dose | 5 (5.0) | 5 (3.6) | |
Completed dose | 26 (25.7) | 29 (21.0) | |
General anesthesia, n (%) | 51 (50.5) | 50 (36.2) | 0.062 |
Local anesthesia, n (%) | 13 (12.9) | 29 (21.0) | |
Conscious sedation, n (%) | 37 (36.6) | 59 (42.8) | |
Left site occlusion, n (%) | 53 (52.5) | 74 (53.6) | 0.861 |
Level of vessel occlusion, n (%) | 0.117 | ||
ICA carotid terminus | 16 (15.8) | 32 (23.2) | |
MCA–M1 | 53 (52.5) | 77 (55.8) | |
MCA–M2 | 32 (31.7) | 29 (21.0) | |
BGC approach used, n (%) | 61 (60.4) | 64 (46.4) | 0.032 |
Non-BGC approach used, n (%) | 40 (39.6) | 74 (53.6) | |
Groin puncture to first run (min), median (IQR) | 6 (4;10) | 6 (5;11) | 0.207 |
Mechanical thrombectomy (min), median (IQR) | 22(10;35) | 39 (23,63) | <0.001 |
Groin puncture to revascularization (min), median (IQR) | 29.5 (17.75;45) | 49.5 (32;80.75) | <0.001 |
FPE, n (%) | 65 (64.4) | 47 (34.1) | <0.001 |
Final number of passes, n (%) | 0.002 | ||
1 | 59 (58.4) | 46 (33.3) | |
2 | 25 (24.8) | 39 (28.3) | |
>2 | 17 (16.8) | 53 (38.3) | |
Final mTICI score, n (%) | <0.001 | ||
Final mTICI ≥2 b, n (%) | 100 (99) | 108 (78.3) | |
Final mTICI ≥2 c, n (%) | 83 (82.2) | 60 (43.5) | |
Symptomatic intracranial hemorrhage, n (%) | 2 (2.0) | 11 (8.0) | 0.044 |
NIHSS score at 24 hours, median (IQR) | 2 (1;6) | 12.5 (7;21) | <0.001 |
Difference of NIHSS from admission to 24 hours, median (IQR) | 9 (4;14) | 1.5 (-1;7) | <0.001 |
Mortality, n (%) | 0 (0) | 56 (46.4) | <0.001 |
ASPECTS, Alberta Stroke Program Early CT Score; BGC, balloon guide catheter; FPE, first-pass effect; IQR, interquartile range; mRS, modified Rankin Scale; mTICI, modified Thrombolysis in Cerebral Infarction; NIHSS, National Institutes of Health Stroke Scale.