Experiment setup, recanalization results, and complications for animal models
| Study | Vascular bed | Clots | Technique | Recanalization rate | Passes to recanalization | Distal embolization | Vasospasm | Acute vessel damage |
| Swine | ||||||||
| Mordasini et al 201122 | IMA, LA | Swine blood + barium | SR | 100% | NA | Absent | 100% | NA |
| Nogueira et al 201223 | IMA, LA | Regular: swine blood + barium, white: swine PRP + barium | SR, SR +A | 100% | Mostly 1 | 6% | 100% | Endothelial denudation, acute inflammation and hemorrhage in adventitia, degeneration of IEL |
| Gory et al 201325 72 | SFA | Swine blood + barium | SR | NA | NA | NA | NA | Endothelial denudation, intimal layer edema, degeneration of IEL, medial edema |
| Yuki et al 201326 | SCA | Swine blood + barium | SR | 75% | 2 | NA | NA | Acute inflammation |
| Shao et al 2014, Zhu et al 201627 28 | LA, SCA, DCA | Swine blood + barium | SR | 94% | Mostly 1 | Absent | 100% | Endothelial denudation, degeneration of IEL |
| Wainwright et al 201673 | ITA, VA | NA | SR | NA | NA | Absent | Absent | Endothelial denudation |
| Jiang et al 201629 | CCA | Swine blood + fibrinogen + iopamidol | SR | 100% | 1.3 | Absent | 9% | Absent |
| Srinivasan et al 201730 | IMA | Swine blood | SR+A | NA | NA | NA | 100% | NA |
| Peschillo et al 201731 | CCA, SCA | Swine blood | DA, SR | DA: 50%, SR: 100% | NA | 25% | 25% | Endothelial denudation, degeneration of IEL and adventitia |
| Ulm et al 201834 | CCA | Red: swine blood + barium, White: swine plasma | SR | 97% | 1.2 | 5% | 100% | Endothelial denudation |
| Jankowitz et al 201974 | IMA, SCA, renal artery | Swine blood | DA | 93%–100% | NA | NA | Present | Endothelial denudation |
| Sanchez et al 202075 | LA, cervical artery | Firm: swine plasma + RBCs Soft: swine blood | SR, SR +A | SR: 77%, SR +A: 100% | SR: 1.9, SR +A: 1.4 | 4% | 62% | NA |
| Simgen et al 202024 | Auxiliary artery | NA | SR | 100% | NA | NA | Absent | Absent |
| Canine | ||||||||
| Park et al 201341 | IMA | Canine blood | SR | 100% | 2 | 40% | Absent | Endothelial denudation |
| Brooks et al 201940 | MCA | Canine blood + fibrinogen | SR | 67% | 1 | NA | 1/6 | NA |
| Rabbit | ||||||||
| Gounis et al 201344 | CCA | Rabbit blood | SR | 0 | NA | NA | NA | Endothelial denudation |
| Arai et al 201645 | CCA | Absent | SR | NA | NA | NA | NA | NA |
APA, ascending pharyngeal artery; CCA, common carotid artery; CoW, circle of Willis; DA, direct aspiration; DCA, deep cervical artery; EC, endothelial cell; ICA, internal carotid artery; IEL, internal elastic lamina; IMA, internal maxillary artery; ITA, internal thoracic artery; LA, lingual artery; MCA, middle cerebral artery; PRP, platelets-rich plasma; RBC, red blood cell; SCA, superficial cervical artery; SFA, superficial femoral artery; SR, stent retriever; SR +A, stent retriever with aspiration; VA, vertebral artery.