Medical management (n=21) | Thrombectomy procedure (n=12) | Odds ratio (95% CI) | P value | |
Maximum documented change in NIHSS* | 7.7±7.0 | 12±5.7 | NA | 0.06 |
Percentage of patients achieving NIHSS ≥10 point improvement or NIHSS ≤4 † | 50 (10/20) | 92 (11/12) | 0.09 (0.01 to 0.84) | 0.0232 |
NIHSS at discharge/day 7 post-randomization of thrombectomy vs MM | 9.9±6.5 | 5.3±6.9 | NA | 0.09 |
Functional independence according to MR vs CT-based selection | ||||
CTP | 29 (6/21) | 67 (8/12) | 0.2 (0.04 to 0.92) | 0.07 |
MRP | 0.0 (0/21) | 0.0 (0/12) | NA | NA |
No perfusion imaging | 14 (3/21) | 8.3 (1/12) | 1.8 (0.2 to 19.9) | 1.00 |
Functional independence according to involved hemisphere | ||||
Right | 50 (4/8) | 100 (5/5) | NA | 0.10 |
Left | 38 (5/13) | 57 (4/7) | 0.47 (0.07 to 3.04) | 0.64 |
Functional independence correlated with following items:‡ | ||||
Location of vascular occlusion | 0.86 | |||
Vascular collateral score | 0.72 | |||
NIHSS | 0.46 | |||
Age | 0.23 | |||
Percentage of patients receiving hemicraniectomy | 0.0 (0/21) | 0.0 (0/12) | NA | NA |
*Multiple comparisons are made without P value adjustment.
†One patient had no NIHSS scores after baseline and was excluded from this analysis.
‡Results from logistics regression model.
CTP, CT perfusion imaging; MM, medical management; MRP, MR perfusion imaging; NIHSS, National Institutes of Health Stroke Scale.