Table 1

Baseline characteristics according to the use of intravenous thrombolysis in overall cohort (main analysis), and in patients treated with carotid artery stenting (secondary analysis)

CharacteristicsOverall
(main analysis)
Carotid artery stenting
(secondary analysis)*
IVT−
(n=222)
IVT+
(n=380)
IVT-
(n=126)
IVT+
(n=214)
Age (years), mean (SD)64.3±13.362.1±12.865.3±13.662.3±11.6
Men144 (64.9)264 (69.5)81 (64.3)144 (67.6)
Medical history
Hypertension124 (55.9)196 (51.6)76 (60.1)118 (55.3)
Diabetes mellitus34 (15.3)52 (13.7)16 (13.1)28 (13.0)
Hypercholesterolemia70 (31.5)124 (32.6)38 (30.2)78 (36.4)
Current smoking75 (33.8)128 (33.7)39 (31.3)74 (34.5)
Stroke event
NIHSS score, median (IQR)16 (12 to 19)16 (12 to 20)16 (11 to 20)16 (10 to 20)
ASPECTS, median (IQR)7 (6 to 8)8 (6 to 9)8 (6 to 9)8 (7 to 9)
Etiology
 Atherosclerosis169 (76.1)269 (70.8)101 (80.2)162 (75.7)
 Dissection53 (23.9)111 (29.2)25 (19.8)52 (24.3)
EVT characteristics
General anesthesia88 (39.6)166 (43.7)62 (49.2)113 (52.9)
First-line strategy
 ADAPT66 (29.7)113 (29.7)267 (21.1)44 (20.3)
 Stent retriever130 (58.6)231 (60.8)82 (65.7)153 (71.7)
 ADAPT + tent retriever25 (11.3)36 (9.5)17 (13.2)17 (7.9)
Carotid artery stenting126 (56.8)214 (56.3)126 (100.0)214 (100.0)
Workflow
Onset to imaging time (min), median (IQR)140 (89 to 250)103 (80 to 145)140 (88 to 225)100 (73 to 144)
Imaging to puncture time (min), median (IQR)91 (59 to 150)107 (65 to 160)86 (60 to 140)101 (68 to 160)
  • Values are expressed as number (%) unless otherwise indicated. Values were calculated after multiple imputation procedure to handle missing data.

  • All parameters in table 1 were included in propensity score calculation.

  • *Secondary analysis included only patients treated with carotid artery stenting.

  • ADAPT, a direct aspiration first pass technique; ASPECTS, Alberta Stroke Program Early CT Score; EVT, endovascular therapy; IVT, intravenous thrombolysis; NIHSS, National Institutes of Health Stroke Scale.