Baseline characteristics according to the use of intravenous thrombolysis in overall cohort (main analysis), and in patients treated with carotid artery stenting (secondary analysis)
| Characteristics | Overall (main analysis) | Carotid artery stenting (secondary analysis)* | ||
| IVT− (n=222) | IVT+ (n=380) | IVT- (n=126) | IVT+ (n=214) | |
| Age (years), mean (SD) | 64.3±13.3 | 62.1±12.8 | 65.3±13.6 | 62.3±11.6 |
| Men | 144 (64.9) | 264 (69.5) | 81 (64.3) | 144 (67.6) |
| Medical history | ||||
| Hypertension | 124 (55.9) | 196 (51.6) | 76 (60.1) | 118 (55.3) |
| Diabetes mellitus | 34 (15.3) | 52 (13.7) | 16 (13.1) | 28 (13.0) |
| Hypercholesterolemia | 70 (31.5) | 124 (32.6) | 38 (30.2) | 78 (36.4) |
| Current smoking | 75 (33.8) | 128 (33.7) | 39 (31.3) | 74 (34.5) |
| Stroke event | ||||
| NIHSS score, median (IQR) | 16 (12 to 19) | 16 (12 to 20) | 16 (11 to 20) | 16 (10 to 20) |
| ASPECTS, median (IQR) | 7 (6 to 8) | 8 (6 to 9) | 8 (6 to 9) | 8 (7 to 9) |
| Etiology | ||||
| Atherosclerosis | 169 (76.1) | 269 (70.8) | 101 (80.2) | 162 (75.7) |
| Dissection | 53 (23.9) | 111 (29.2) | 25 (19.8) | 52 (24.3) |
| EVT characteristics | ||||
| General anesthesia | 88 (39.6) | 166 (43.7) | 62 (49.2) | 113 (52.9) |
| First-line strategy | ||||
| ADAPT | 66 (29.7) | 113 (29.7) | 267 (21.1) | 44 (20.3) |
| Stent retriever | 130 (58.6) | 231 (60.8) | 82 (65.7) | 153 (71.7) |
| ADAPT + tent retriever | 25 (11.3) | 36 (9.5) | 17 (13.2) | 17 (7.9) |
| Carotid artery stenting | 126 (56.8) | 214 (56.3) | 126 (100.0) | 214 (100.0) |
| Workflow | ||||
| Onset to imaging time (min), median (IQR) | 140 (89 to 250) | 103 (80 to 145) | 140 (88 to 225) | 100 (73 to 144) |
| Imaging to puncture time (min), median (IQR) | 91 (59 to 150) | 107 (65 to 160) | 86 (60 to 140) | 101 (68 to 160) |
Values are expressed as number (%) unless otherwise indicated. Values were calculated after multiple imputation procedure to handle missing data.
All parameters in table 1 were included in propensity score calculation.
*Secondary analysis included only patients treated with carotid artery stenting.
ADAPT, a direct aspiration first pass technique; ASPECTS, Alberta Stroke Program Early CT Score; EVT, endovascular therapy; IVT, intravenous thrombolysis; NIHSS, National Institutes of Health Stroke Scale.