Table 1

Infarct core volume, penumbral volume and mismatch ratio evaluated with RAPID for simulations with and without artificial movement

Scenario	Simulated ground truth			Evaluated with RAPID
	Simulated ground truth			No movement			Subtle movement			Strong movement
	Core (mL)	Penumbra (mL)	MR	Core (mL)	Penumbra (mL)	MR	Core (mL)	Penumbra (mL)	MR	Core (mL)	Penumbra (mL)	MR
a	9	105	11.7	0	111	inf	0	145	inf	4	115	28.8
b	27	105	3.9	20	108	5.4	20	122	6.1	20	139	7.0
c	36	105	2.9	29	107	3.7	24	125	5.2	24	172	7.2
d	52	105	2.0	52	103	2.0	50	102	2.0	40	175	4.4
e	59	105	1.8	59	100	1.7	58	102	1.8	53	143	2.7
f	63	105	1.7	60	99	1.7	57	115	2.0	62	116	1.9
g	73	105	1.4	70	97	1.4	73	93	1.3	67	121	1.8

In this analysis, four critical classifications occurred (bold), when applying the DEFUSE-3 target mismatch criterion.1
MR, mismatch ratio.