Outcomes | No IVT (n=282) | IVT (n=242) | Unadjusted | Adjusted* | ||
OR (95% CI) | p-value | OR (95% CI) | p-value | |||
Favorable outcome | 33/256 (12.9) | 47/204 (23.0) | 2.02 (1.24 to 3.31) | 0.005 | 1.82 (0.98 to 3.38) | 0.058 |
Death at 3 months | 105/261 (40.2) | 78/209 (37.3) | 0.88 (0.61 to 1.29) | 0.52 | 0.88 (0.53 to 1.47) | 0.63 |
Any hemorrhage | 128/247 (51.8) | 112/202 (55.4) | 1.24 (0.84 to 1.82) | 0.28 | 1.34 (0.85 to 2.09) | 0.20 |
sICH | 30/247 (12.1) | 34/202 (16.8) | 1.56 (0.91 to 2.68) | 0.11 | 1.89 (0.97 to 3.67) | 0.062 |
PH | 29/244 (11.9) | 34/200 (17.0) | 1.52 (0.89 to 2.60) | 0.13 | 3.20 (1.56 to 6.54) | 0.005 |
Per procedural complication | 61/277 (22.0) | 61/236 (25.8) | 1.24 (0.82 to 1.88) | 0.30 | 1.25 (0.76 to 2.06) | 0.38 |
Values expressed as number (percentage) unless otherwise indicated. P-values and ORs (95% CIs) calculated using mixed logistic regression model including center as random effect. Favorable outcome defined as a 90-day mRS score of 0 to 2, or equal to pre-stroke mRS score.
*OR adjusted on presepcified factors as age, antithrombotic use, initial NIHSS and ASPECT score, occlusion site and delay between onset to puncture, direct admission and mRS pre-stroke score<2.
ASPECT, Alberta Stroke Program Early CT; IVT, intravenous thrombolysis; mRS, modfied Rankin Scale; NIHSS, National Institutes of Health Stroke Scale.