Table 1

Cohort demographic characteristics, medical history, and clinical data before and after propensity score matched analysis.

VariableUnmatched cohortP valuePropensity score matched cohortP value
Age ≥90 years
(n=26)
Age <90 years
(n=188)
d* Age ≥90 years
(n=23)
Age <90 years
(n=66)
d*
Patient demographics and comorbidities
Sex (female)21 (80.8)100 (53.2)61.30.0118 (78.3)47 (71.2)16.30.59
Atrial fibrillation12 (46.2)69 (36.7)19.30.359 (39.1)29 (43.9)−9.80.69
Coronary artery disease9 (34.6)62 (33.0)3.50.877 (30.4)25 (37.9)−15.70.52
Chronic kidney disease8 (30.8)38 (20.2)24.40.226 (26.1)19 (28.8)−6.10.80
Diabetes3 (11.5)52 (27.7)−41.50.103 (13.0)16 (24.2)−29.10.38
Heart valve disease2 (7.7)10 (5.3)9.60.641 (4.3)3 (4.5)−1.01.00
Hyperlipidemia12 (46.2)89 (47.3)−2.40.9110 (43.5)33 (50.0)−13.10.59
Hypertension22 (84.6)145 (77.1)19.10.4619 (82.6)56 (84.8)−6.10.75
Mechanical heart valve0 (0)10 (5.3)−33.50.610 (0)0 (0)1.00
Previous myocardial infarction2 (7.7)11 (5.9)7.30.661 (4.3)3 (4.5)−1.01.00
Smoker (current)0 (0)36 (19.1)−68.80.010 (0)0 (0)1.00
Patient characteristics
NIHSS14 (10–20)16 (11–19)−4.60.4214 (10–18)14 (10–19)−7.40.76
Transferred from spoke hospital10 (38.5)67 (35.6)5.80.788 (34.8)25 (37.9)−6.40.79
IV alteplase prior to EVT9 (34.6)47 (25.0)21.10.318 (34.8)22 (33.3)3.10.90
Location and volume
Hemisphere of LVO (left)11 (42.3)102 (54.3)0.259 (39.1)31 (47.0)0.52
Vessel of LVO0.610.69
 ICA5 (19.2)38 (20.2)5 (21.7)9 (13.6)
 Tandem0 (0.0)9 (4.8)0 (0.0)2 (3.0)
 M114 (53.8)104 (55.3)13 (56.5)40 (60.6)
 M27 (26.9)37 (19.7)5 (21.7)15 (22.7)
Ischemic core (mL)†2.5 (0–14)7 (0–23)−25.40.256 (0–24)0 (0–12)14.30.44
Mismatch volume72 (45–102)71 (45–110)−2.70.9371 (42–81)66 (45–105)−2.40.91
Procedure
Door to groin puncture85 (34–132)81 (52–109)23.50.4987 (37–128)84 (48–116)20.50.46
Recanalization after first pass18 (69.2)105 (55.9)27.90.2015 (65.2)38 (57.6)15.70.52
Complications1 (3.8)2 (1.6)0.321 (4.3)1 (1.5)0.45
Failed EVT‡0 (0.0)9 (4.8)0.600 (0.0)3 (4.5)0.57
  • All values are n (%) or median (IQR).

  • Proportion P values assessed by chi square or Fisher’s exact test as appropriate. Nonparametric measures assessed by Mann–Whitney test.

  • *Standardized difference.

  • †Defined as volume of blood flow <30% by computed tomography perfusion imaging.

  • ‡Defined as Thrombolysis in Cerebral Infarction (TICI) score of 0.

  • EVT, endovascular thrombectomy; ICA, internal carotid artery; IQR, interquartile range; IV, intravenous; LVO, large vessel occlusion; MI, myocardial infarction; NIHSS, National Institutes of Health Stroke Scale.