Imaging characteristics of 617 patients with a stroke*
| First pass reperfusion (n=205) | Non-first pass reperfusion (n=282) | No reperfusion (n=130) | P value (FP vs non-FP) | |
| ASPECTS, median (IQR) | 8 (7–9) | 8 (6–9) | 7 (6–9) | 0.420 |
| Favorable collateral Maas score | 145 (71.1) | 185 (66.1) | 83 (63.8) | 0.243 |
| COVES | 0.011 | |||
| 0 | 26 (12.7) | 41 (14.6) | 24 (18.5) | |
| 1 | 36 (17.6) | 80 (28.6) | 40 (30.4) | |
| 2 | 39 (19.1) | 57 (20.4) | 35 (26.9) | |
| 3 | 59 (28.8) | 53 (18.7) | 19 (14.6) | |
| 4 | 37 (18.1) | 34 (12.1) | 8 (6.2) | |
| 5 | 8 (3.9) | 15 (5.4) | 3 (2.3) | |
| 6 | 0 (0) | 2 (0.7) | 1 (0.8) | |
| Favorable VO profiles (COVES ≥3) | 97 (47.4) | 107 (37.9) | 35 (26.7) | 0.005 |
| Unfavorable VO profiles (COVES <2) | 108 (52.6) | 175 (62.1) | 95 (73.3) | <0.001 |
| Baseline estimated ischemic core volume (CBF <30%) (mL), median (IQR) | 8.5 (0–30) | 10 (0–31) | 13 (0–41) | 0.478 |
| Penumbra Tmax >6 s volume (mL), median (IQR) | 115 (69–169) | 128 (75–187) | 114 (62–160) | 0.050 |
| Location of vessel occlusion | <0.001 | |||
| Internal carotid artery | 25 (12.3) | 76 (27.1) | 33 (25.4) | |
| MCA 1 segment occlusion | 138 (67.6) | 169 (60.4) | 67 (51.5) | |
| MCA 2/distal segment occlusion | 41 (20.1) | 35 (12.5) | 30 (23.1) | |
*Data are No. and frequencies (%), unless otherwise indicated.
ASPECTS, Alberta Stroke Program Early CT Score; CBF, cerebral blood flow; CO, cortical vein opacification score ; FP, first pass reperfusion; MCA, middle cerebral artery; Tmax, Time-to-maximum of the residue function; VO, venous outflow.