Table 2

Association between patient characteristics, stroke presentation and clinical outcome by logistic regression models (n=169)

Description*Models with event: Final mRS >2
TotalFinal mRS ≤2Final mRS >2Reference or unitUnivariate modelsMultivariate model 1Multivariate model 2
169 (100%)99 (100%)70 (100%)OR (95% CI)P valueOR (95% CI)P valueOR (95% CI)P value
Age, years74.4 (64.5–82.4)71.3 (61.2–79.2)77.7 (72.3–84.7)51.23 (1.08 to 1.41)0.00231.257 (1.065 to 1.501)0.00871.254 (1.050 to 1.516)0.0151
NIHSS total score at baseline17(12–21)13(9–18)20.5 (17–24)11.19 (1.12 to 1.28)<0.00011.149 (1.063 to 1.250)0.00071.121 (1.032 to 1.224)0.0083
Initial occlusion site on initial imaging, ICA41 (24%)15 (15%)26 (67%)No ICA3.31 (1.61 to 7.02)0.00143.027 (1.195 to 7.998)0.02142.789 (1.068 to 7.608)0.0392
Baseline core volume, mL16.2 (6.8–54.3)11.7 (5.7–25.1)28.1 (12.7–97.6)101.15 (1.07 to 1.24)0.00021.040 (0.936 to 1.163)0.47361.011 (0.904 to 1.135)0.8480
Baseline Tmax >6 s volume, mL99 (67.9–138.2)88.6 (56.3–119.6)116.6 (88.2–164.2)101.11 (1.05 to 1.18)0.0003xx
HIR0.46 (0.33–0.6)0.41 (0.3–0.56)0.51 (0.36–0.68)0.11.14 (1.00 to 1.31)0.0615xx
No Mismatch23 (14%)8 (8%)15 (21%)Mismatch3.10 (1.26 to 8.15)0.01604.873 (1.096 to 22.806)0.03844.988 (1.049 to 25.409)0.0457
Treated with IV-tPA118 70%)76 (77%)42 (60%)No0.45 (0.23 to 0.88)0.02050.739 (0.310 to 1.769)0.49250.698 (0.286 to 1.702)0.4254
SBP at arrival in the cath lab, mmHg150 (135–170)145 (130–160)153.5 (140–180)101.24 (1.09 to 1.41)0.00121.128 (0.957 to 1.336)0.15411.118 (0.940 to 1.337)0.2111
General anesthesia67 (40%)2 (26%)41 (59%)No3.97 (2.09 to 7.72)<0.00012.227 (0.970 to 5.171)0.05932.710 (1.135 to 6.649)0.0261
Duration of the procedure, min35 (23–54)30 (22–51)40 (25–56)51.02 (0.97 to 1.08)0.35441.051 (0.979 to 1.124)0.14721.053 (0.979 to 1.128)0.1419
Hemorrhagic Transformation at 24 hours95 (56%)39 (39%)56 (80%)No6.15 (3.09 to 12.90)<0.0001x3.640 (1.523 to 9.096)0.0043
  • *Effective with percentage (N (%)) for qualitative variables and median with IQR for quantitative variable.

  • cath lab, catheterization laboratory; HIR, hypoperfusion intensity ratio; ICA, internal carotid artery; IV-tPA, intravenous tissue plasminogen activator; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressure.