Baseline characteristics and periprocedural results
| IVT ongoing at FLR n=180 | IVT finished at FLR n=1123 | P value | |
| Age (years), mean±SD | 71.8±14.5 | 71.9±13.4 | 0.94 |
| Female sex, % (n) | 48.3 (87) | 48.1 (540) | 1.0 |
| Prestroke mRS, median (IQR) | 0 (0–0) | 0 (0–1) | 0.74 |
| NIHSS, median (IQR) | 14 (7–18) | 14 (9–18) | 0.06 |
| ASPECTS, median (IQR) | 10 (8–10) | 9 (8-10) | 0.015 |
| Cardiovascular risk factors, % (n) | |||
| Hypertension | 41.7 (75) | 38.5 (430) | 0.46 |
| Diabetes | 70.9 (127) | 73.0 (815) | 0.59 |
| Dyslipidemia | 15.6 (28) | 20.8 (232) | 0.11 |
| Atrial fibrillation | 40.0 (72) | 33.9 (379) | 0.13 |
| Current smoking | 15.8 (27) | 16.7 (170) | 0.83 |
| Referral for ET, % (n) | 7.8 (14) | 46.0 (517) | <0.001 |
| Thrombectomy maneuvers (IQR) | 1 (1–2) | 2 (1–3) | <0.001 |
| Time intervals (min), median (IQR) | |||
| Symptom onset to IVT | 92.5 (80-135) | 90 (70–125) | 0.055 |
| Symptom onset to groin | 117 (100–149) | 180.5 (140-240) | <0.001 |
| IVT to FLR | 47 (39–53) | 128 (91–180) | <0.001 |
| Groin to FLR | 22 (15–30) | 41 (26–61) | <0.001 |
| Symptom onset to FLR | 141 (121–176) | 229 (185–290) | <0.001 |
| Complications, % (n) | |||
| Device malfunction | 0.6 (1) | 0.1 (1) | 0.26 |
| Dissection or perforation | 1.7 (3) | 1.8 (20) | 1.0 |
| ICH after 24 hours | 6.1 (11) | 14.8 (166) | 0.001 |
| Symptomatic ICH | 1.1 (2) | 3.9 (43) | 0.08 |
ASPECTS, Alberta Stroke Program Early CT Score; FLR, flow restoration; ICH, intracranial hemorrhage; IVT, intravenous thrombolysis; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale.