Ongoing IVT on flow restoration predicts functional outcome in multivariable analysis
mRS at discharge | mRS at 90 days | |||||
aOR | 95% CI | P value | aOR | 95% CI | P value | |
Age | 0.96 | 0.95 to 0.97 | <0.001 | 0.95 | 0.94 to 0.96 | <0.001 |
Female sex | 1.22 | 0.96 to 1.54 | 0.10 | 0.94 | 0.74 to 1.19 | 0.62 |
NIHSS | 0.89 | 0.87 to 0.91 | <0.001 | 0.90 | 0.88 to 0.92 | <0.001 |
ASPECTS | 1.25 | 1.16 to 1.35 | <0.001 | 1.23 | 1.14 to 1.33 | <0.001 |
Diabetes | 0.46 | 0.35 to 0.61 | <0.001 | 0.44 | 0.33 to 0.59 | <0.001 |
SO to flow restoration, hours | 0.85 | 0.79 to 0.92 | <0.001 | 0.84 | 0.77 to 0.91 | <0.001 |
Premorbid mRS | 0.65 | 0.58 to 0.73 | <0.001 | 0.64 | 0.57 to 0.71 | <0.001 |
Ongoing IVT | 1.61 | 1.13 to 2.30 | 0.009 | 1.52 | 1.06 to 2.18 | 0.025 |
Retrieval attempts | 0.77 | 0.71 to 0.84 | <0.001 | 0.82 | 0.75 to 0.89 | <0.001 |
aOR, adjusted OR; ASPECTS, Alberta Stroke Program Early CT Score; IVT, intravenous thrombolysis; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; SO, symptom onset.