Table 4

Main study results

MSIG
(n=12)
CG1
(n-10)
P valueCG2
(n=25)
P value
NIHSS score at admission; median (IQR)14.0 (5–22)15.5 (5–24)0.888*16.0 (4–22)0.757*
NIHSS score after 24 hours; median (IQR)7.0 (0–21)16.0 (2–23)0.241*14.0 (3–25)0.158*
NIHSS at day 7 (alive only); median (IQR)3.0 (0–19)13 (2–19)0.502*14 (2–35)0.110*
mRS score 0–2 prior to stroke; n (%)12 (100.0)9 (90.0)0.910†25 (100.0)1.000
mRS score 3 prior to stroke; n (%)0 (0.0)1 (10.0)0.910†0 (0.0)1.000
mRS score 0–1 at day 90; n (%)6 (50.0)1 (10.0)0.148†2 (8.0)0.016†
mRS score 0–2 at day 90; n (%)7 (58.3)1 (10.0)0.062†3 (12.0)0.012†
mRS score 0–3 at day 90; n (%)7 (58.3)2 (20.0)0.198†4 (16.0)0.036†
mRS score 4–5 at day 90; n (%)1 (8.3)2 (20.0)0.667†15 (60.0)0.003†
Death within 7 days; n (%)0 (0.0)3 (30.0)0.156†0 (0.0)1.000
Death within 90 days; n (%)4 (33.3)6 (60.0)0.782†6 (24.0)1.000†
Cerebral edema; n (%)0 (0.0)3 (30.0)0.156†4 (16.0)0.564†
Decompressive craniectomy; n (%)0 (0.0)0 (0.0)1.000†1 (4.0)1.000†
sICH; n (%)0 (0.0)0 (0.0)1.000†1 (4.0)1.000†
  • *Mann-Whitney U-test;

  • †Fisher’s exact test;

  • CG1, control group in center 1; CG2, control group in center 2; mRS, modified Rankin scale; MSIG, microsurgical intervention group; NIHSS, National Institutes of Health Stroke Scale; sICH, symptomatic intracerebral hemorrhage.