Baseline characteristics categorized based on recanalization and functional outcomes following endovascular thrombectomy
| Total cohort (n=128) | Recanalization grade (mTICI) | P value | Functional outcome (mRS) | P value | |||
| Complete (TICI 2c,3) (n=83) | Non-complete (TICI 0–2b) (n=45) | Good (mRS 0–2) (n=48) | Poor (mRS 3–6) (n=80) | ||||
| Demographics and comorbidities | |||||||
| Age (years) (mean (SD)) | 66.9 (11.8) | 68.5 (10.5) | 64 (13.4) | 0.11 | 65.8 (11.2) | 67.6 (12.1) | 0.43 |
| Sex (men) (n (%)) | 83 (65) | 52 (63) | 31 (69) | 0.56 | 30 (63) | 53 (66) | 0.71 |
| Diabetes mellitus (n (%)) | 19 (15) | 16 (19) | 3 (7) | 0.07 | 5 (10) | 14 (18) | 0.32 |
| Hypertension (n (%)) | 77 (60) | 55 (66) | 22 (49) | 0.06 | 26 (54) | 51 (64) | 0.38 |
| Hypercholesterolemia (n (%)) | 30 (23) | 18 (22) | 12 (27) | 0.52 | 12 (25) | 18 (23) | 0.83 |
| Active smoking (n (%)) | 41 (32) | 26 (31) | 15 (33) | 0.85 | 17 (35) | 24 (30) | 0.56 |
| Atrial fibrillation (n (%)) | 27 (21) | 17 (20) | 10 (22) | 0.82 | 8 (17) | 19 (24) | 0.38 |
| History of stroke/TIA (n (%)) | 23 (18) | 16 (19) | 7 (16) | 0.81 | 10 (21) | 13 (16) | 0.64 |
| Antiaggregants (n (%)) | 52 (41) | 35 (42) | 17 (38) | 0.71 | 21 (44) | 31 (39) | 0.58 |
| Clinicoimaging features | |||||||
| Initial NIHSS score (median (IQR)) | 15 (10–25) | 15 (9 to 23) | 15 (10–32.5) | 0.91 | 13 (7–18) | 18 (11–40) | 0.02 |
| Intravenous rt-PA (n (%)) | 46 (36) | 31 (37) | 15 (33) | 0.71 | 23 (48) | 23 (29) | 0.04 |
| Clot location | 0.35 | 0.19 | |||||
| Baseline PC-ASPECTS (median (IQR)) | 7 (6–8) | 7 (6–8) | 7 (5.5–8) | 0.98 | 8 (6–8) | 7 (5–8) | 0.006 |
| PC-CS (median (IQR)) | 5 (4–6) | 5 (4–6) | 5 (4–6) | 0.90 | 5 (4–7) | 5 (3–6) | 0.03 |
| Etiology of ischemic stroke* | 0.11 | 0.17 | |||||
| Onset to imaging (min) (median (IQR)) | 243 (150–365) | 234 (137 to 359) | 280 (167–410) | 0.25 | 213 (117–341) | 263 (156–410) | 0.11 |
| Imaging to puncture (min) (median (IQR)) | 108 (60–224) | 110 (60 to 222) | 88 (55–232) | 0.95 | 97 (51–171) | 133 (69–246) | 0.06 |
| Procedural time (min) (median (IQR)) | 50 (26–84) | 45 (25–74) | 60 (31–111) | 0.007 | 51 (25–93) | 50 (27–73) | 0.47 |
| Procedural details | |||||||
| EVT technique (CA) (n (%)) | 33 (26) | 21 (25) | 12 (27) | 0.87 | 14 (29) | 19 (24) | 0.50 |
| EVT technique (SR) (n (%)) | 35 (27) | 20 (24) | 15 (33) | 0.26 | 12 (25) | 23 (29) | 0.64 |
| EVT technique (combined SR+CA) (n (%)) | 35 (27) | 28 (34) | 7 (16) | 0.03 | 14 (29) | 21 (26) | 0.72 |
| EVT technique (switch) (n (%)) | 25 (20) | 14 (17) | 11 (24) | 0.30 | 8 (17) | 17 (21) | 0.53 |
| No of passes (median (IQR)) | 1 (1–2) | 1 (1 to 2) | 2 (1–3) | 0.02 | 1 (1–2) | 1.5 (1–3) | 0.14 |
| Adjuvant angioplasty (n (%)) | 8 (6) | 5 (6) | 3 (7) | >0.99 | 2 (4) | 6 (8) | 0.71 |
| Rescue stenting (n (%)) | 17 (13) | 13 (16) | 4 (9) | 0.41 | 7 (15) | 10 (13) | 0.79 |
| Final reperfusion (n (%)) | |||||||
| mTICI grade 0–2a | 19 (15) | 5 (10) | 14 (18) | 0.32 | |||
| mTICI grade 2b | 26 (20) | 6 (13) | 20 (25) | 0.11 | |||
| mTICI grade 2c, 3 | 83 (65) | 37 (77) | 46 (57) | 0.03 | |||
| FPE | 43 (34) | 18 (38) | 25 (31) | 0.5 | |||
*Three patients with different etiologies were excluded.
EVT, endovascular thrombectomy; FPE, first pass effect; mRS, modified Rankin Scale; mTICI, modified Treatment in Cerebral Infarction; NIHSS, National Institutes of Health Stroke Scale; PC-ASPECTS, posterior circulation Alberta Stroke Programme Early CT Score; PC-CS, posterior circulation collateral score; rt-PA, recombinant tissue plasminogen activator; TIA, transient ischemic attack.