Patients’ baseline, procedural and outcome characteristics
| Baseline, procedural and outcome characteristics | Intravenous treatment with alteplase, n=290 | No intravenous treatment, n=139 | P values |
| Median age, years (IQR) | 72 (60–79) | 75 (66–81) | 0.02* |
| Female sex, n (%) | 161 (56) | 81 (58) | 0.31 |
| Median admission NIHSS (IQR) | 19 (16–22) | 18 (15–21) | 0.36 |
| Median ASPECTS (IQR) | 4 (3–5) | 4 (3–5) | 0.64 |
| Median time from onset to imaging, minutes (IQR) | 119 (78–156) | 139 (98–165) | 0.32 |
| MT, n (%) | 90 (31) | 78 (56) | <0.001 |
| mTICI 2b–3, n (%) | 68 (76) | 53 (68) | 0.36 |
| sICH, n (%) | 37 (13) | 5 (4) | 0.004* |
| Median mRS at 90 days, (IQR) | 5 (4–6) | 5 (4–6) | 0.06 |
| mRS 0–2, n (%) | 43 (15) | 21 (15) | 0.91 |
| mRS 5–6, n (%) | 168 (58) | 88 (63) | 0.41 |
| Mortality, n (%) | 99 (34) | 65 (47) | 0.069 |
*Indicates significance.
ASPECTS, Alberta Stroke Programme Early CT Score; mRS, modified Rankin Scale; MT, mechanical thrombectomy; mTICI, modified Thrombolysis in Cerebral Infarction; NIHSS, National Institutes of Health Stroke Scale; sICH, symptomatic intracranial hemorrhage.