Effect estimates for the association between the interventionist’s experience in the preceding year (EXPfreq), per 10 procedures, and clinical, radiological, and workflow outcomes
| EE | Unadjusted (95% CI) | Adjusted (95% CI) | |
| Clinical outcomes | |||
| NIHSS score at 24–48 hours | β | −0.57 (−0.82 to -0.31) | −0.46 (−0.70 to −0.21) |
| mRS score at 90 days | cOR | 1.03 (0.98 to 1.07) | 1.01 (0.95 to 1.07) |
| Mortality at 90 days | OR | 0.97 (0.91 to 1.03) | 0.97 (0.90 to 1.04) |
| Safety outcomes | |||
| Occurrence any SAEs* | OR | 0.86 (0.82 to 0.91) | 0.88 (0.82 to 0.95) |
| Stroke progression† | OR | 0.92 (0.84 to 1.01) | 0.88 (0.80 to 0.98) |
| New ischemic stroke† | OR | 1.01 (0.83 to 1.24) | 1.00 (0.80 to 1.27) |
| Symptomatic ICH* | OR | 1.00 (0.90 to 1.12) | 0.98 (0.87 to 1.09) |
| Imaging outcomes | |||
| Postinterventional eTICI score† | cOR | 1.17 (1.12 to 1.23) | 1.15 (1.07 to 1.23) |
| Recanalization† | OR | 1.22 (1.15 to 1.29) | 1.20 (1.11 to 1.31) |
| Safety outcomes scored on DSA | |||
| Occurrence of procedural complications* | OR | 0.98 (0.92 to 1.06) | 0.95 (0.86 to 1.05) |
| Dissection† | OR | 0.89 (0.73 to 1.09) | 0.89 (0.71 to 1.11) |
| Perforation† | OR | 1.07 (0.89 to 1.29) | 1.06 (0.87 to 1.30) |
| Embolus new territory† | OR | 0.95 (0.85 to 1.08) | 0.96 (0.84 to 1.09) |
| Distal thrombus† | OR | 1.06 (0.99 to 1.14) | 1.12 (1.02 to 1.22) |
| Vasospasm† | OR | 1.03 (0.93 to 1.15) | 1.04 (0.92 to 1.18) |
| Workflow outcomes | |||
| Number of attempts† | β | 0.02 (−0.02 to 0.07) | 0.02 (−0.04 to 0.08) |
| Duration procedure (min)‡ | β | −2.34 (−3.26 to -1.42) | −3.08 (−4.32 to −1.84) |
*Additionally adjusted for: clot burden score; ICA stenosis/dissection/occlusion; antiplatelet/DOAC/coumarin/heparin use.
†Additionally adjusted for: clot burden score; ICA stenosis/dissection/occlusion.
‡Additionally adjusted for: clot burden score; ICA stenosis/dissection/occlusion; ICA stent placement; general anesthesia.
cOR, common odds ratio; DOAC, direct oral anticoagulant; DSA, digital subtraction angiography; EE, effect estimate; eTICI, extended Thrombolysis in Cerebral Infarction scale; ICA, internal carotid artery; ICH, intracranial hemorrhage; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; SAE, serious adverse event.