Factor | Level | Men | Women | P value |
N | 65 | 65 | ||
Age, median (IQR) | 64 (54–74) | 67 (52– 76) | 0.56α | |
Serum glucose (mg/dL), median (IQR) | 120 (107–157) | 125 (108–154) | 0.78α | |
Hypertension | 43/65 (66%) | 46/65 (71%) | 0.57β | |
Congestive heart failure | 7/65 (11%) | 5/65 (8%) | 0.54β | |
Coronary artery disease | 9/65 (14%) | 12/65 (18%) | 0.47β | |
Atrial fibrillation | 19/65 (29%) | 17/65 (26%) | 0.70β | |
Diabetes mellitus | 15/65 (23%) | 16/65 (25%) | 0.84β | |
Transient ischemic attack | 4/65 (6%) | 4/64 (6%) | >0.99γ | |
Prior stroke | 9/65 (14%) | 8/63 (13%) | 0.85β | |
Current smokers | 9/61 (15%) | 7/62 (11%) | 0.57β | |
Past smokers | 11/60 (18%) | 11/62 (18%) | 0.93β | |
Clot location | ICA | 9/65 (14%) | 10/65 (15%) | 0.38β |
MCA-M1 | 35/65 (54%) | 41/65 (63%) | ||
MCA-M2 | 21/65 (32%) | 14/65 (22%) | ||
Transfer status | 26/65 (40%) | 27/65 (42%) | 0.86β | |
Time from last known well to arrival to EVT-capable center (hours), median (IQR) | 2.23 (0.75–3.83) | 2.40 (1.10– 4.33) | 0.22α | |
IV Alteplase administered | 41/65 (63%) | 41/65 (63%) | 1.00β | |
NIHSS score, median (IQR) | 15 (12–20) | 16 (10–20) | 0.76α | |
ASPECTS on baseline CT, median (IQR) | 8 (7–9) | 8 (7–9) | 0.71α | |
Ischemic core volume (mL), median (IQR) | 6 (0–21) | 12 (0–25) | 0.30α | |
Tissue volume with Tmax >6 s (mL), median (IQR) | 131.0 (94.0–200.1) | 109.0 (66.0–141.0) | 0.007α | |
Tissue volume with Tmax >10 s (mL), median (IQR) | 68.7 (28.4–121.2) | 43 (20–73.7) | 0.044α | |
Collateral score | 0 | 4/65 (6%) | 1/65 (2%) | 0.60γ |
1 | 30/65 (46%) | 32/65 (49%) | ||
2 | 23/65 (35%) | 22/65 (34%) | ||
3 | 3/65 (5%) | 6/65 (9%) | ||
4 | 5/65 (8%) | 4/65 (6%) | ||
Modified collateral score | 0 | 4/65 (6%) | 1/65 (2%) | 0.73γ |
1 | 30/65 (46%) | 32/65 (49%) | ||
2 | 16/65 (25%) | 16/65 (25%) | ||
3 | 7/65 (11%) | 6/65 (9%) | ||
4 | 3/65 (5%) | 6/65 (9%) | ||
5 | 5/65 (8%) | 4/65 (6%) | ||
Collateral score, median (IQR) | 1 (1–2) | 1 (1–2) | 0.62α | |
Modified collateral score, median (IQR) | 1 (1–2) | 1 (1–2) | 0.65α | |
Modified collateral score 0–2 vs 3–5 | 0–2 | 50/65 (77%) | 49/65 (75%) | 0.84β |
3–5 | 15/65 (23%) | 16/65 (25%) | ||
Modified collateral score 0–1 vs 2–5 | 0–1 | 34/65 (52%) | 33/65 (51%) | 0.86β |
2–5 | 31/65 (48%) | 32/65 (49%) | ||
Hypoperfusion intensity ratio, median (IQR) | 0.48 (0.31–0.63) | 0.42 (0.30–0.56) | 0.44α | |
Hypoperfusion intensity ratio >0.4 | 37/65 (57%) | 37/65 (57%) | 1.00β | |
Time from last known well to procedure (hours), median (IQR) | 3.80 (2.28–5.23) | 3.83 (2.70–5.98) | 0.36α | |
No. of passes | Single | 31/64 (48%) | 27/63 (43%) | 0.53β |
Multiple | 33/64 (52%) | 36/63 (57%) | ||
Type of anesthesia | General Anesthesia | 27/65 (42%) | 26/65 (40%) | 0.86β |
Conscious Sedation | 38/65 (58%) | 39/65 (60%) | ||
Time from groin puncture to successful reperfusion/end of procedure (Minutes), median (IQR) | 32 (21–56) | 39 (30–59) | 0.052α |
Results are shown as No (%) unless stated otherwise.
α - Wilcoxon rank-sum test, β - Pearson’s χ2 test, γ - Fisher’s Exact test
ASPECTS, Alberta Stroke Program Early CT Score; ICA, internal carotid artery; MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale.