Clinical outcomes at 90 days
Characteristics | All patients | SMT | EVT | Unadjusted OR (95% CI) | P value | Adjusted OR* (95% CI) | P value |
Outcomes at 90 days, n (%) | |||||||
mRS score at 90 days, (median (IQR)) | 5.0 (3.0–6.0) | 6.0 (5.0–6.0) | 5.0 (3.0–6.0) | 2.37 (1.05 to 5.37)† | 0.038 | 2.68 (1.16 to 6.20)† | 0.022 |
mRS score 0–3 at 90 days | 31 (25.8) | 3 (10.7) | 28 (30.4) | 3.65 (1.02 to 13.08) | 0.047 | 3.85 (1.05 to 14.10) | 0.042 |
mRS score 0–2 at 90 days | 24 (20.0) | 1 (3.6) | 23 (25.0) | 9.00 (1.16 to 69.98) | 0.036 | 11.01 (1.34 to 90.49) | 0.026 |
mRS score 0–1 at 90 days | 20 (16.7) | 1 (3.6) | 19 (20.7) | 7.03 (0.89 to 55.07) | 0.063 | 7.91 (0.96 to 64.97) | 0.054 |
Mortality at 90 days | 55 (45.8) | 17 (60.7) | 38 (41.3) | 0.46 (0.19 to 1.08) | 0.074 | 0.35 (0.13 to 0.90) | 0.03 |
sICH at 48 hours | 7 (5.9) | 0 (0.0) | 7 (7.7) | NA | 0.998 | NA | 0.998 |
*The multiple logistic regression test was used to analyze ORs. Outcomes at 90 days used adjusted variables: age, NIHSS baseline, diabetes mellitus.
†Common OR; the primary analysis involved 92 patients in the EVT group and 28 patients in the SMT group. Scores on the mRS of functional disability range from 0 (no symptoms) to 6 (death). The common OR was estimated from an ordinal logistic regression model and indicates the odds of improvement of 1 point on the mRS, with a common OR >1 favoring the endovascular treatment.
EVT, endovascular treatment; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; OR, odds ratio; sICH, symptomatic intracranial hemorrhage; SMT, standard medical treatment.