Comparison of clinical characteristics and outcomes among patients presenting with acute ischemic stroke due to carotid or vertebral artery dissections
| Characteristic | Vertebral Artery Dissection, N = 2,562 | Carotid Artery Dissection, N = 2,789 | p-value1 |
|---|---|---|---|
| Age (years), Mean (SD) | 53 (17) | 57 (17) | <0.001 |
| Female, n (%) | 1,027 (40%) | 1,151 (41%) | 0.4 |
| Traumatic Brain Injury, n (%) | 39 (1.5%) | 89 (3.2%) | <0.001 |
| APR-DRG Mortality Risk Score, Mean (SD) | 2 (1) | 2 (1) | 0.2 |
| APR-DRG Illness Severity Score, Mean (SD) | 2 (1) | 2 (1) | 0.6 |
| Treatment | |||
| Thrombolytic Treatment, n (%) | 169 (6.6%) | 349 (13%) | <0.001 |
| Mechanical Thrombectomy, n (%) | 126 (4.9%) | 539 (19%) | <0.001 |
| Stent placement, n (%) | 57 (2.2%) | 353 (13%) | <0.001 |
| Comorbidities | |||
| Hypertension, n (%) | 1,364 (53%) | 1,439 (52%) | 0.2 |
| Diabetes Mellitus, n (%) | 563 (22%) | 594 (21%) | 0.5 |
| Chronic Kidney Disease, n (%) | 160 (6.2%) | 236 (8.5%) | 0.002 |
| Congestive Heart Failure, n (%) | 128 (5.0%) | 205 (7.4%) | <0.001 |
| Inpatient Complications and Outcomes | |||
| Intracerebral/Subarachnoid Hemorrhage, n (%) | 145 (5.7%) | 313 (11%) | <0.001 |
| Length of Stay (Days), Median (IQR) | 4 (2, 8) | 5 (3, 10) | <0.001 |
| Total Charges ($), Median (IQR) | 54,110 (30,297, 110,062) | 93,485 (43,406, 199,121) | <0.001 |
| Adverse Discharge, n (%) | 1,402 (55%) | 1,842 (66%) | <0.001 |
1 Wilcoxon rank sum test; Pearson’’s Chi-squared test