Hemorrhage distribution across the treatment groups
| Heading | Overall (n (%)) | Treatment | OR (95% CI) | P value | |
| Intravenous alteplase and EVT (n (%)) (n=292） | EVT-only (n (%)) (n=299) | ||||
| Any hemorrhage | 254 (43.0) | 134 (45.9) | 120 (40.1) | 1.27 (0.91 to 1.75) | 0.16 |
| Symptomatic ICH | 32 (5.4) | 20 (6.8) | 12 (4.0) | 1.90 (0.90 to 3.99) | 0.095 |
| Asymptomatic ICH | 222 (37.6) | 114 (39.0) | 108 (36.1) | 1.20 (0.85 to 1.68) | 0.30 |
| Hemorrhage type* | |||||
| HI-1 | 12 (2.1) | 6/287 (2.1) | 6/297 (2.0) | 1.13 (0.36 to 3.58) | 0.83 |
| HI-2 | 127 (21.7) | 61/287 (21.3) | 66/297 (22.1) | 1.05 (0.70 to 1.58) | 0.83 |
| HI total | 139 (23.8) | 67/287 (23.3) | 72/297 (24.2) | 1.05 (0.71 to 1.56) | 0.79 |
| PH-1 | 34 (5.8) | 20/287 (7.0) | 14/297 (4.7) | 1.62 (0.79 to 3.31) | 0.19 |
| PH-2 | 50 (8.6) | 31/287 (10.8) | 19/297 (6.4) | 1.85 (1.01 to 3.40) | 0.048 |
| PH total | 84 (14.4) | 51/287 (17.8) | 33/297 (11.1) | 1.75 (1.08 to 2.85) | 0.024 |
| Extra-parenchymal hemorrhage | 24 (4.1) | 11/287 (3.8) | 13/297 (4.4) | 0.96 (0.42 to 2.20) | 0.92 |
| No hemorrhage | 337 (57.0) | 158 (55.1) | 179 0.3) | 1 | |
*ICH Heidelberg Bleeding Classification subtype information was lost in 7 patients, 5 in intravenous alteplase and EVT group and 2 in EVT-only group.
aICH, asymptomatic intracranial hemorrhage; CI, confidence interval; EVT, endovascular thrombectomy; HI, hemorrhagic infarction; ICH, intracranial hemorrhage; OR, odds ratio; PH, parenchymal hematoma; sICH, symptomatic intracranial hemorrhage.