Characteristics | Univariate analysis | Multivariate analysis | ||||
P value | Crude HR | 95% CI | P value | Adjusted HR | 95% CI | |
Male | 0.128 | 1.456 | 0.897 to 2.363 | – | – | – |
Age >54 years | 0.023 | 0.559 | 0.338 to 0.924 | 0.006 | 0.464 | 0.274 to 0.785 |
BMI ≥28 kg/m2 | 0.048 | 0.399 | 0.161 to 0.994 | 0.026 | 0.427 | 0.184 to 0.991 |
Diabetes mellitus | 0.721 | 1.165 | 0.504 to 2.697 | – | – | – |
Dyslipidemia | 0.408 | 0.812 | 0.495 to 1.331 | – | – | – |
Hypertension | 0.728 | 1.089 | 0.673 to 1.762 | – | – | – |
Pre-SAH | 0.886 | 0.919 | 0.288 to 2.929 | – | – | – |
Pre-stroke | 0.786 | 1.152 | 0.416 to 3.189 | – | – | – |
Coronary artery disease | 0.677 | 1.195 | 0.517 to 2.765 | – | – | – |
Current smoking | 0.225 | 1.456 | 0.794 to 2.671 | – | – | – |
Regular alcohol drinkers | 0.777 | 1.098 | 0.575 to 2.096 | – | – | – |
Allergy | 0.131 | 0.523 | 0.226 to 1.212 | – | – | – |
Number of PEDs used | 0.864 | 0.937 | 0.446 to 1.969 | – | – | – |
PED associated with coils | 0.813 | 1.060 | 0.653 to 1.721 | – | – | – |
Aneurysm location in posterior circulation | 0.002 | 2.175 | 1.335 to 3.543 | P<0.001 | 2.895 | 1.732 to 4.838 |
Aneurysm with lobulation | 0.590 | 1.225 | 0.585 to 2.564 | – | – | – |
Aneurysm with daughter sac | 0.943 | 0.967 | 0.389 to 2.408 | – | – | – |
Aneurysm in bifurcation | 0.157 | 1.933 | 0.776 to 4.816 | – | – | – |
Aneurysm neck | 0.109 | 1.020 | 0.995 to 1.046 | – | – | – |
Maximum diameter | 0.124 | 1.018 | 0.995 to 1.042 | – | – | – |
Aneurysm height | 0.164 | 1.023 | 0.991 to 1.057 | – | – | – |
Aneurysm width | 0.058 | 1.022 | 0.999 to 1.046 | – | – | – |
Aneurysm perpendicular height | 0.106 | 1.028 | 0.994 to 1.063 | – | – | – |
Aspect ratio | 0.219 | 0.800 | 0.561 to 1.142 | – | – | – |
Height/width ratio | 0.040 | 0.387 | 0.157 to 0.956 | – | – | – |
Bottle neck factor | 0.578 | 0.810 | 0.385 to 1.702 | – | – | – |
Size ratio | 0.030 | 1.081 | 1.008 to 1.160 | – | – | – |
Neck ratio | 0.006 | 1.130 | 1.035 to 1.235 | – | – | – |
Parental artery diameter | 0.557 | 1.089 | 0.819 to 1.447 | – | – | – |
Proximal artery diameter | 0.485 | 1.099 | 0.843 to 1.434 | – | – | – |
Distal artery diameter | 0.395 | 1.132 | 0.851 to 1.505 | – | – | – |
Difference between proximal and distal artery | 0.929 | 0.986 | 0.732 to 1.330 | – | – | – |
Proximal/distal ratio | 0.958 | 0.977 | 0.407 to 2.343 | – | – | – |
Mean artery diameter | 0.382 | 1.147 | 0.843 to 1.561 | – | – | – |
Recurrent aneurysm | 0.713 | 1.303 | 0.319 to 5.331 | – | – | – |
Symptomatic aneurysm | 0.736 | 1.086 | 0.672 to 1.756 | – | – | – |
Multiple aneurysm | 0.327 | 0.760 | 0.439 to 1.316 | – | – | – |
Unsatisfactory device deployment | 0.160 | 1.923 | 0.772 to 4.79 | – | – | – |
Balloon angioplasty | 0.030 | 1.771 | 1.056 to 2.968 | 0.037 | 1.992 | 1.162 to 3.414 |
Preinterventional operation | 0.370 | 0.588 | 0.185 to 1.874 | – | – | – |
Last follow-up complete occlusion | 0.494 | 0.782 | 0.386 to 1.584 | – | – | – |
Fusiform aneurysm | 0.004 | 2.062 | 1.258 to 3.380 | – | – | – |
Drug withdrawal | 0.116 | 1.641 | 0.932 to 2.903 | – | – | – |
Clopidogrel switched to ticagrelor | 0.256 | 1.457 | 0.762 to 2.789 | – | – | – |
BMI, body mass index; ISS, in-stent stenosis; PED, Pipeline embolization device; SAH, subarachnoid hemorrhage.