Follow-Up characteristics of patients after Pipeline embolization device (PED) treatment
| Characteristics | Non-ISS (n=390) | ISS (n=69) | Total (n=459) | P value |
| Postoperative complications | 5 (1.3%) | 3 (4.3%) | 8 (1.7%) | 0.195 |
| First follow-up time | 7 (5–9) | 6 (5–7) | 6 (5–8) | 0.026 |
| First follow-up parental artery diameter | 3.12 (2.60–3.66) | 1.65 (0.50–2.32) | 2.95 (2.32–3.53) | <0.001 |
| First follow-up aneurysm complete occlusion | 306 (78.5%) | 53 (76.8%) | 359 (78.2%) | 0.760 |
| Last follow-up time | 9 (6–16) | 12 (6–19) | 9 (6–16) | 0.116 |
| Last follow-up parental artery diameter | 3.12 (2.55–3.66) | 1.16 (0–1.80) | 2.90 (2.26–3.56) | <0.001 |
| Last follow-up aneurysm complete occlusion | 320 (82.1%) | 60 (87.0%) | 380 (82.8%) | 0.320 |
| Severe postoperative symptoms* related to ISS | 0 (0%) | 5 (7.2%) | 5 (1.1%) | – |
| Mortality related to ISS (basilar artery occlusion) | 0 (0%) | 2 (2.9%) | 2 (0.4%) | – |
| Drug withdrawal | 82 (21.0%) | 21 (30.4%) | 103 (22.4%) | 0.116 |
| Clopidogrel switched to ticagrelor | 58 (14.9%) | 14 (20.3%) | 72 (15.7%) | 0.254 |
*Severe postoperative symptoms included hemidysesthesia, hemiplegia, and hemianopia.
ISS, in-stent stenosis.