Multivariate analysis for heparin bolus administration during endovascular treatment in anterior circulation stroke patients receiving intravenous thrombolysis (IVT+) or not (IVT–).
| Parameter | ACS patients | |
| IVT+ | IVT– | |
| OR (95% CI; p-value) | OR (95% CI; p-value) | |
| mRS shift at 3 months* | 2.40 (1.34 to 5.06; <0.05) | 1.00 (0.55 to 1.81; 1.00) |
| Mortality* | 3.73 (0.87 to 15.91; 0.08) | 1.12 (0.50 to 2.49; 0.78) |
| TICI 2b-3† | 0.88 (0.21 to 3.72; 0.86) | 0.40 (0.13 to 1.22; 0.11) |
| ICH at 24 hours‡ | 0.40 (0.13 to 1.26; 0.12) | 1.13 (0.42 to 3.07; 0.81) |
*Ordinal and logistic regression analyses adjusted for age, sex, pmRS, NIHSS, SO to door, door to groin, SO to IVT (IVT+ group only), ASPECTS, successful reperfusion, and overall complications.
†Binary logistic regression analysis adjusted for age, pmRS, NIHSS, ASPECTS, SO to door, door to groin, SO to IVT (IVT+ group only), and retrieval attempts.
‡Binary logistic regression analysis adjusted for age, pmRS, NIHSS, SO to door, door to groin, SO to IVT (IVT+ group only), retrieval attempts, and successful reperfusion.
ASPECTS, Alberta Stroke Program Early CT Score; CI, confidence interval; ICH, intracranial hemorrhage; IVT, intravenous thrombolysis; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; OR, odds ratio; pmMS, premodified Rankin Scale; SO, stroke onset; TICI, Thrombolysis In Cerebral Infarction.