NIHSS score in patients enrolled in large ischemic core trials
| RESCUE-Japan LIMIT (EVT vs MM) | SELECT2 (EVT vs MM) | ASPECT-ANGEL (EVT vs MM) | |
| NIHSS at time of randomization, target | ≥6 | N/A | 6–30 |
| NIHSS, actual enrollment (median) | 22 vs 22 | 19 vs 19 | 16 vs 15 |
| TESLA | LASTE | TENSION | |
| NIHSS at time of randomization, target | >6 | ≥6 | <26 |
| NIHSS, actual enrollment (median) | 19 vs 18 | 21 vs 21 | 19 vs 18 |
EVT, endovascular therapy; MM, medical management; NIHSS, National Institutes of Health Stroke Scale.