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C-arm flat detector computed tomography: the technique and its applications in interventional neuro-radiology

  • Interventional Neuroradiology
  • Published:
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Abstract

Introduction

Flat detector computed tomography (FDCT) is an imaging tool that generates three-dimensional (3-D) volumes from data obtained during C-arm rotation using CT-like reconstruction algorithms. The technique is relatively new and, at current levels of performance, lags behind conventional CT in terms of image quality. However, the advantage of its availability in the interventional room has prompted neuro-radiologists to identify clinical settings where its role is uniquely beneficial.

Methods

We performed a search of the online literature databases to identify studies reporting experience with FDCT in interventional neuro-radiology. The studies were systematically reviewed and their findings grouped according to specific clinical situation addressed.

Results

FDCT images allow detection of procedural complications, evaluation of low-radiopacity stents and assessment of endosaccular coil packing in intra-cranial aneurysms. Additional roles are 3-D angiography that provides an accurate depiction of vessel morphology with low concentrations of radiographic contrast media and a potential for perfusion imaging due to its dynamic scanning capability. A single scan combining soft tissue and angiographic examinations reduces radiation dose and examination time. Ongoing developments in flat detector technology and reconstruction algorithms are expected to further enhance its performance and increase this range of applications.

Conclusion

FDCT images provide useful information in neuro-interventional setting. If current research confirms its potential for assessing cerebral haemodynamics by perfusion scanning, the combination would redefine it as an invaluable tool for interventional neuro-radiology procedures. This facility and its existing capabilities of parenchymal and angiographic imaging would also extend its use to the triage of acute stroke patients.

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References

  1. Orth R, Wallace M, Kuo M (2008) C-arm cone-beam CT: general principles and technical considerations for use in interventional radiology. J Vasc Interv Radiol 19:814–820

    Article  PubMed  Google Scholar 

  2. Grass M, Koppe R, Klotz E et al (1999) Three-dimensional reconstruction of high contrast objects using C-arm image intensifier projection data. Comput Med Imaging Graph 23:311–321

    Article  CAS  PubMed  Google Scholar 

  3. Linsenmaier U, Rock C, Euler E et al (2002) Three-dimensional CT with a modified C-arm image intensifier: feasibility. Radiology 224:286–292

    Article  PubMed  Google Scholar 

  4. Kalender W, Kyriakou Y (2007) Flat-detector computed tomography (FD-CT). Eur Radiol 17:2767–2779

    Article  PubMed  Google Scholar 

  5. Neitzel U (2005) Status and prospects of digital detector technology for CR and DR. Radiat Prot Dosim 114:32–38

    Article  CAS  Google Scholar 

  6. Wallace M, Kuo M, Glaiberman C et al (2008) Three-dimensional C-arm cone-beam CT: applications in the interventional suite. J Vasc Interv Radiol 19:799–813

    Article  PubMed  Google Scholar 

  7. Fahrig R, Fox AJ, Lownie S et al (1997) Use of a C-arm system to generate true three-dimensional computed rotational angiograms: preliminary in vitro and in vivo results. AJNR Am J Neuroradiol 18:1507–1514

    CAS  PubMed  Google Scholar 

  8. Akpek S, Brunner T, Benndorf G, Strother C (2005) Three-dimensional imaging and cone beam volume CT in C-arm angiography with flat panel detector. Diagn Interv Radiol 11:10–13

    PubMed  Google Scholar 

  9. Cowen A, Davies A, Sivananthan M (2008) The design and imaging characteristics of dynamic, solid-state, flat-panel x-ray image detectors for digital fluoroscopy and fluorography. Clin Radiol 63:1073–1085

    Article  CAS  PubMed  Google Scholar 

  10. Gupta R, Grasruck M, Suess C et al (2006) Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization. Eur Radiol 16:1191–1205

    Article  PubMed  Google Scholar 

  11. Kyriakou Y, Kalender W (2007) X-ray scatter data for flat-panel detector CT. Phys Med 23:3–15

    Article  PubMed  Google Scholar 

  12. Buhk J, Lingor P, Knauth M (2008) Angiographic CT with intravenous administration of contrast medium is a noninvasive option for follow-up after intracranial stenting. Neuroradiology 50:349–354

    Article  PubMed  Google Scholar 

  13. Gröschel K, Schnaudigel S, Pilgram S et al (2009) A systematic review on outcome after stenting for intracranial atherosclerosis. Stroke 40:e340–e347. doi:10.1161/STROKEAHA.108.532713

    Article  PubMed  Google Scholar 

  14. Suh D, Kim J, Choi J et al (2008) Intracranial stenting of severe symptomatic intracranial stenosis: results of 100 consecutive patients. AJNR Am J Neuroradiol 29:781–785

    Article  CAS  PubMed  Google Scholar 

  15. Higashida R, Smith W, Gress D et al (1997) Intravascular stent and endovascular coil placement for a ruptured fusiform aneurysm of the basilar artery. Case report and review of the literature. J Neurosurg 87:944–949

    Article  CAS  PubMed  Google Scholar 

  16. Wakhloo A, Mandell J, Gounis M et al (2008) Stent-assisted reconstructive endovascular repair of cranial fusiform atherosclerotic and dissecting aneurysms: long-term clinical and angiographic follow-up. Stroke 39:3288–3296

    Article  PubMed  Google Scholar 

  17. Akpek S, Arat A, Morsi H et al (2005) Self-expandable stent-assisted coiling of wide-necked intracranial aneurysms: a single-center experience. AJNR Am J Neuroradiol 26:1223–1231

    PubMed  Google Scholar 

  18. Yoo E, Kim DJ, Kim DI et al (2009) Bailout stent deployment during coil embolization of intracranial aneurysms. AJNR Am J Neuroradiol 30:1028–1034

    Article  CAS  PubMed  Google Scholar 

  19. Levy E, Mehta R, Gupta R et al (2007) Self-expanding stents for recanalization of acute cerebrovascular occlusions. AJNR Am J Neuroradiol 28:816–822

    CAS  PubMed  Google Scholar 

  20. Sadasivan C, Cesar L, Seong J et al (2009) An original flow diversion device for the treatment of intracranial aneurysms: evaluation in the rabbit elastase-induced model. Stroke 40:952–958

    Article  PubMed  Google Scholar 

  21. Riedel C, Tietke M, Alfke K et al (2009) Subacute stent thrombosis in intracranial stenting. Stroke 40:1310–1314

    Article  PubMed  Google Scholar 

  22. Fiorella D, Chow M, Anderson M et al (2007) A 7-year experience with balloon-mounted coronary stents for the treatment of symptomatic vertebrobasilar intracranial atheromatous disease. Neurosurgery 61:236–242 discussion 242–233

    Article  PubMed  Google Scholar 

  23. Zaidat O, Klucznik R, Alexander M et al (2008) The NIH registry on use of the Wingspan stent for symptomatic 70–99% intracranial arterial stenosis. Neurology 70:1518–1524

    Article  CAS  PubMed  Google Scholar 

  24. Honda Y, Fitzgerald P (2003) Stent thrombosis: an issue revisited in a changing world. Circulation 108:2–5

    Article  PubMed  Google Scholar 

  25. Benndorf G, Strother C, Claus B et al (2005) Angiographic CT in cerebrovascular stenting. AJNR Am J Neuroradiol 26:1813–1818

    PubMed  Google Scholar 

  26. Ebrahimi N, Claus B, Lee C et al (2007) Stent conformity in curved vascular models with simulated aneurysm necks using flat-panel CT: an in vitro study. AJNR Am J Neuroradiol 28:823–829

    CAS  PubMed  Google Scholar 

  27. Trossbach M, Hartmann M, Braun C et al (2004) Small vessel stents for intracranial angioplasty: in vitro evaluation of in-stent stenoses using CT angiography. Neuroradiology 46:459–463

    Article  CAS  PubMed  Google Scholar 

  28. Willinsky R, Taylor S, TerBrugge K et al (2003) Neurologic complications of cerebral angiography: prospective analysis of 2,899 procedures and review of the literature. Radiology 227:522–528

    Article  PubMed  Google Scholar 

  29. Richter G, Engelhorn T, Struffert T et al (2007) Flat panel detector angiographic CT for stent-assisted coil embolization of broad-based cerebral aneurysms. AJNR Am J Neuroradiol 28:1902–1908

    Article  CAS  PubMed  Google Scholar 

  30. Li M, Gao B, Fang C et al (2006) Angiographic follow-up of cerebral aneurysms treated with Guglielmi detachable coils: an analysis of 162 cases with 173 aneurysms. AJNR Am J Neuroradiol 27:1107–1112

    PubMed  Google Scholar 

  31. Piotin M, Spelle L, Mounayer C et al (2007) Intracranial aneurysms: treatment with bare platinum coils—aneurysm packing, complex coils, and angiographic recurrence. Radiology 243:500–508

    Article  PubMed  Google Scholar 

  32. Buhk J, Kallenberg K, Mohr A et al (2009) Evaluation of angiographic computed tomography in the follow-up after endovascular treatment of cerebral aneurysms—a comparative study with DSA and TOF-MRA. Eur Radiol 19:430–436

    Article  PubMed  Google Scholar 

  33. van Rooij W, Sluzewski M, Beute G et al (2006) Procedural complications of coiling of ruptured intracranial aneurysms: incidence and risk factors in a consecutive series of 681 patients. AJNR Am J Neuroradiol 27:1498–1501

    PubMed  Google Scholar 

  34. Gallas S, Drouineau J, Gabrillargues J et al (2008) Feasibility, procedural morbidity and mortality, and long-term follow-up of endovascular treatment of 321 unruptured aneurysms. AJNR Am J Neuroradiol 29:63–68

    Article  CAS  PubMed  Google Scholar 

  35. Cloft H, Kallmes D (2002) Cerebral aneurysm perforations complicating therapy with Guglielmi detachable coils: a meta-analysis. AJNR Am J Neuroradiol 23:1706–1709

    PubMed  Google Scholar 

  36. Li M, Gao B, Fang C et al (2006) Prevention and management of intraprocedural rupture of intracranial aneurysm with detachable coils during embolization. Neuroradiology 48:907–915

    Article  PubMed  Google Scholar 

  37. Engelhorn T, Struffert T, Richter G et al (2008) Flat panel detector angiographic CT in the management of aneurysmal rupture during coil embolization. AJNR Am J Neuroradiol 29:1581–1584

    Article  CAS  PubMed  Google Scholar 

  38. Heran N, Song J, Namba K et al (2006) The utility of DynaCT in neuroendovascular procedures. AJNR Am J Neuroradiol 27:330–332

    CAS  PubMed  Google Scholar 

  39. Struffert T, Richter G, Engelhorn T et al (2009) Visualisation of intracerebral haemorrhage with flat-detector CT compared to multislice CT: results in 44 cases. Eur Radiol 19:619–625

    Article  PubMed  Google Scholar 

  40. Söderman M, Babic D, Holmin S et al (2008) Brain imaging with a flat detector C-arm: technique and clinical interest of XperCT. Neuroradiology 50:863–868

    Article  PubMed  Google Scholar 

  41. Arakawa H, Marks M, Do H et al (2008) Experimental study of intracranial hematoma detection with flat panel detector C-arm CT. AJNR Am J Neuroradiol 29:766–772

    Article  CAS  PubMed  Google Scholar 

  42. Doelken M, Struffert T, Richter G et al (2008) Flat-panel detector volumetric CT for visualization of subarachnoid hemorrhage and ventricles: preliminary results compared to conventional CT. Neuroradiology 50:517–523

    Article  CAS  PubMed  Google Scholar 

  43. White P, Gilmour J, Weir N et al (2008) AngioCT in the management of neurointerventional patients: a prospective, consecutive series with associated dosimetry and resolution data. Neuroradiology 50:321–330

    Article  PubMed  Google Scholar 

  44. Ernemann U, Grönewäller E, Duffner F et al (2003) Influence of geometric and hemodynamic parameters on aneurysm visualization during three-dimensional rotational angiography: an in vitro study. AJNR Am J Neuroradiol 24:597–603

    PubMed  Google Scholar 

  45. Jou L, Mohamed A, Lee D et al (2007) 3D rotational digital subtraction angiography may underestimate intracranial aneurysms: findings from two basilar aneurysms. AJNR Am J Neuroradiol 28:1690–1692

    Article  PubMed  Google Scholar 

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Acknowledgements

We thank Siemens for providing the hardware and software support.

Conflict of interest statement

MK is funded by The Rhodes Trust. JVB is supported by the Oxford Biomedical Research Centre.

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Correspondence to Mudassar Kamran.

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Kamran, M., Nagaraja, S. & Byrne, J.V. C-arm flat detector computed tomography: the technique and its applications in interventional neuro-radiology. Neuroradiology 52, 319–327 (2010). https://doi.org/10.1007/s00234-009-0609-5

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  • DOI: https://doi.org/10.1007/s00234-009-0609-5

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