Original investigationHemodynamics and Rupture of Terminal Cerebral Aneurysms
Section snippets
Patients and Images
A total of 42 consecutive terminal cerebral aneurysms were selected from our database for this study. Patients referred to the interventional neuroradiological service of the Inova Fairfax Hospital (Virginia) between 2003 and 2005, and diagnosed with cerebral aneurysms by conventional catheter angiograms and three-dimensional rotational angiography were considered. Rotational angiography images were obtained during a 180° rotation and imaging at 15 frames per second for a total of 8 seconds, by
Results
It was found that in average ruptured aneurysms had larger MWSS than unruptured aneurysms. In particular, the MWSS averaged over the ruptured aneurysm group (271 dyn/cm2) exceeded by a factor larger than two that of the unruptured group (118 dyn/cm2). A t-test showed that the difference is significant at 95% of confidence level (P = .04). It was also observed that 90% of the aneurysms with MWSS higher than 250 dyn/cm2 were ruptured. Two aneurysms, one in the middle cerebral artery and one in
Conclusion
Cerebral aneurysms are pathological dilations of the arterial wall frequently located near arterial bifurcations in the circle of Willis 25, 26, 27. The most serious consequence is their rupture and intracranial hemorrhage, with an associated high mortality and morbidity rate 28, 29, 30, 31. Intracranial aneurysms are particularly difficult to treat, and often do not produce symptoms before they rupture (32). Improvements of neuroradiological techniques have resulted in more frequent detection
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Pathophysiology of intracranial aneurysms in monozygotic twins: A rare case study from hemodynamic perspectives
2023, Computers in Biology and MedicineResearch on the effect of visceral artery Aneurysm's cardiac morphological variation on hemodynamic situation based on time-resolved CT-scan and computational fluid dynamics
2022, Computer Methods and Programs in BiomedicineCitation Excerpt :Hemodynamic parameters, especially wall shear stress (WSS) and oscillatory shear index (OSI), which are massively explored and quantitatively used to demonstrate the pathogenic mechanism of aneurysms, are also obtained from individual cardiac phase images CFD approach [6–8]. Recent research pointed out a controversy exists when WSS and OSI values obtained from individual medical image CFD analysis are clinically used [9–12,40–42]. Both high and low values have been shown to correlate with aneurysms [42].
Exploration of blood flow patterns in cerebral aneurysms during the cardiac cycle
2018, Computers and Graphics (Pergamon)Citation Excerpt :In contrast, type two with vortical flow was mainly seen in ruptured aneurysms together with small impingement regions and small jets. Castro et al. [33] correlated rupture to inflow jet structure and peak WSS. Nakayama et al. [34] classified systolic flow in cerebral aneurysms dependent on their rotational position.
Proximal Stenosis Is Associated with Rupture Status in Middle Cerebral Artery Aneurysms
2018, World NeurosurgeryHemodynamic characterization of geometric cerebral aneurysm templates
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Supported by Philips Medical Systems, American Heart Association.