Neuropediatrics 2009; 40(3): 126-128
DOI: 10.1055/s-0029-1238306
Short Communication

© Georg Thieme Verlag KG Stuttgart · New York

Neurological Outcome and Risk of Recurrence Depending on the Anterior vs. Posterior Arterial Distribution in Children with Stroke

A. Touré1 , 2 , S. Chabrier3 , 4 , M. D. Plagne3 , E. Presles4 , V. des Portes1 , C. Rousselle1
  • 1Hospices civils de Lyon, Service de neuropédiatrie, Hôpital femme-mère-enfant, Bron, France
  • 2Centre hospitalier universitaire de Bamako, Service de pédiatrie, hôpital Gabriel Touré, Bamako, Mali
  • 3Centre hospitalier universitaire de Saint-Etienne, Service de pédiatrie, Hôpital nord, Saint-Etienne, France
  • 4Inserm, CIE3, Saint-Etienne, France
Further Information

Publication History

received 14.01.2009

accepted 07.08.2009

Publication Date:
17 December 2009 (online)

Abstract

We report the outcome of 46 previously healthy children with arterial ischemic stroke. After a mean follow-up of 26 months, five (11%) children suffered a recurrence and 28 (61%) were left with sequelae. The prevalence and the severity of the sequelae were similar irrespective of whether the localization of the accident was anterior or posterior. However, a recurrence was significantly more frequent in the posterior than in the anterior group (4/14 vs. 1/32; p=0.025). These observations may lead to the establishment of therapeutic guidelines according to the localization of the infarct.

References

  • 1 Amlie-Lefond C, Sébire G, Fullerton HJ. Recent developments in childhood arterial ischaemic stroke.  Lancet Neurol. 2008;  7 425-435
  • 2 Braun KP, Bulder MM, Chabrier S. et al . The course and outcome of unilateral intracranial arteriopathy in 79 children with ischaemic stroke.  Brain. 2009;  132 544-557
  • 3 Chabrier S, Husson B, Lasjaunias P. et al . Stroke in childhood: outcome and recurrence risk by mechanism in 59 patients.  J Child Neurol. 2000;  15 290-294
  • 4 Danchaivijitr N, Cox TC, Saunders DE. et al . Evolution of cerebral arteriopathies in childhood arterial ischemic stroke.  Ann Neurol. 2006;  59 620-626
  • 5 Fullerton HJ, Johnston SC, Smith WS. Arterial dissection and stroke in children.  Neurology. 2002;  57 1155-1160
  • 6 Fullerton HJ, Wu YW, Sidney S. et al . Risk of recurrent childhood arterial ischemic stroke in a population-based cohort: the importance of cerebrovascular imaging.  Pediatrics. 2007;  119 495-501
  • 7 Ganesan VFJ, Chong WK, Cox TC. et al . Posterior circulation stroke in childhood: risk factor and recurrence.  Neurology. 2002;  59 1552-1556
  • 8 Ganesan V, Prengler M, Wade A. et al . Clinical and radiological recurrence after childhood ischemic stroke.  Circulation. 2006;  114 2170-2177
  • 9 Lanthier S, Armstrong D, Domi T. et al . Post-Varicella arteriopathy of childhood.  Natural history of vascular stenosis. Neurology. 2005;  64 660-663
  • 10 Lanthier S, Carmant, David M. et al . Stroke in children: The coexistence of multiple risk factors predicts poor outcome.  Neurology. 2000;  54 371-378
  • 11 Sébire G, Fullerton H, Riou E. et al . Toward the definition of cerebral arteriopathies of childhood.  Curr Opin Pediatr. 2004;  16 617-622
  • 12 Wraige E, Pohl KR, Ganesan V. A proposed classification for subtypes of arterial ischaemic stroke in children.  Dev Med Child Neurol. 2005;  47 252-256

Correspondence

Stephane Chabrier

Centre hospitalier universitaire de Saint-Etienne

Service de pédiatrie

Hôpital nord

42055 Saint-Etienne

France

Phone: +33/477/828 729

Fax: +33/477/828 108

Email: stephane.chabrier@chu-st-etienne.fr

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