Osmotic blood-brain barrier disruption: a new means of increasing chemotherapeutic agent delivery

Trans Am Neurol Assoc. 1979:104:256-60.

Authors

E A Neuwelt, E P Frenkel, J T Diehl, K R Maravilla, L H Vu, W K Clark, S I Rapoport, P A Barnett, S A Hill, S E Lewis, A L Ehle, C W Beyer Jr, R J Moore

PMID: 121949

No abstract available

MeSH terms

Animals
Blood-Brain Barrier*
Brain Neoplasms / drug therapy*
Dogs
Humans
Hypertonic Solutions
Mannitol / administration & dosage*
Methotrexate / administration & dosage*

Substances

Hypertonic Solutions
Mannitol
Methotrexate