Object: An experimental study was performed to determine the biomechanical end-mounting configurations that replicate in vivo physiological motion of the cervical spine in a multiple-level human cadaveric model. The vertebral motion response for the modified testing protocol was compared to in vivo motion data and traditional pure-moment testing methods.
Methods: Biomechanical tests were performed on fresh human cadaveric cervical spines (C2-T1) mounted in a programmable testing apparatus. Three different end-mounting conditions were studied: pinned-pinned, pinned-fixed, and translational/pinned-fixed. The motion response of the individual segmental vertebral rotations was statistically compared using one-way analysis of variance and Student-Newman-Keuls tests (p < 0.05 unless otherwise stated) to determine differences in the motion responses for different testing methods.
Conclusions: A translational/pinned-fixed mounting configuration induced a bending-moment distribution across the cervical spine, resulting in a motion response that closely matched the in vivo case. In contrast, application of pure-moment loading did not reproduce the physiological response and is less suitable for studying disc arthroplasty and nonfusion devices.