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The administration of rtPA before mechanical thrombectomy in acute ischemic stroke patients is associated with a significant reduction of the retrieved clot area but it does not influence revascularization outcome.
Rossi R, Fitzgerald S, Molina S, Mereuta OM, Douglas A, Pandit A, Santos AMS, Murphy B, Alderson J, Brennan P, Power S, O'Hare A, Gilvarry M, McCarthy R, Psychogios K, Magoufis G, Tsivgoulis G, Nagy A, Vadász Á, Szikora I, Jood K, Redfors P, Nordanstig A, Ceder E, Dehlfors N, Dunker D, Tatlisumak T, Rentzos A, Thornton J, Doyle KM. Rossi R, et al. Among authors: dehlfors n. J Thromb Thrombolysis. 2021 Feb;51(2):545-551. doi: 10.1007/s11239-020-02279-1. Epub 2020 Sep 16. J Thromb Thrombolysis. 2021. PMID: 32936433 Free PMC article.
Large Artery Atherosclerotic Clots are Larger than Clots of other Stroke Etiologies and have Poorer Recanalization rates.
Fitzgerald S, Rossi R, Mereuta OM, Molina S, Okolo A, Douglas A, Jabrah D, Pandit A, McCarthy R, Gilvarry M, Ceder E, Dehlfors N, Dunker D, Nordanstig A, Redfors P, Jood K, Magoufis G, Psychogios K, Tsivgoulis G, Alderson J, O'Hare A, Power S, Brennan P, Nagy A, Vadász Á, Brinjikji W, Kallmes D, Szikora I, Tatlisumak T, Rentzos A, Thornton J, Doyle KM. Fitzgerald S, et al. Among authors: dehlfors n. J Stroke Cerebrovasc Dis. 2021 Jan;30(1):105463. doi: 10.1016/j.jstrokecerebrovasdis.2020.105463. Epub 2020 Nov 24. J Stroke Cerebrovasc Dis. 2021. PMID: 33242780 Free PMC article.
Per-pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted clot area and histological composition.
Fitzgerald S, Rossi R, Mereuta OM, Jabrah D, Okolo A, Douglas A, Molina Gil S, Pandit A, McCarthy R, Gilvarry M, Dunker D, Nordanstig A, Ceder E, Redfors P, Jood K, Dehlfors N, Magoufis G, Tsivgoulis G, Brinjikji W, Kallmes DF, O'Hare A, Power S, Brennan P, Alderson J, Nagy A, Vadász Á, Psychogios K, Szikora I, Tatlisumak T, Rentzos A, Thornton J, Doyle KM. Fitzgerald S, et al. Among authors: dehlfors n. J Neurointerv Surg. 2021 Dec;13(12):1111-1116. doi: 10.1136/neurintsurg-2020-016966. Epub 2020 Dec 9. J Neurointerv Surg. 2021. PMID: 33298510 Free PMC article.
Platelet-rich emboli are associated with von Willebrand factor levels and have poorer revascularization outcomes.
Douglas A, Fitzgerald S, Mereuta OM, Rossi R, O'Leary S, Pandit A, McCarthy R, Gilvarry M, Holmegaard L, Abrahamsson M, Jerndal M, Dehlfors N, Brennan P, Power S, O'Hare A, Griffin E, Kallmes DF, Brinjikji W, Szikora I, Tatlisumak T, Rentzos A, Thornton J, Doyle K. Douglas A, et al. Among authors: dehlfors n. J Neurointerv Surg. 2020 Jun;12(6):557-562. doi: 10.1136/neurintsurg-2019-015410. Epub 2019 Nov 4. J Neurointerv Surg. 2020. PMID: 31685695