Y-stent coiling of basilar bifurcation aneurysms induces a dynamic angular vascular remodeling with alteration of the apical wall shear stress pattern

B Gao, MI Baharoglu, AD Cohen, AM Malek - Neurosurgery, 2013 - journals.lww.com
BACKGROUND: Although wide-necked basilar bifurcation aneurysms are treated with Y-
stent coiling, the effect of this intervention on vessel configuration and hemodynamics is …

Vascular change measured with independent component analysis of dynamic susceptibility contrast MRI predicts bevacizumab response in high-grade glioma

PS LaViolette, AD Cohen, MA Prah, SD Rand… - Neuro …, 2013 - academic.oup.com
Background Standard pre-and postcontrast (T1+ C) anatomical MR imaging is proving to be
insufficient for accurately monitoring bevacizumab treatment response in recurrent …

Realistic non-Newtonian viscosity modelling highlights hemodynamic differences between intracranial aneurysms with and without surface blebs

JE Hippelheuser, A Lauric, AD Cohen… - Journal of biomechanics, 2014 - Elsevier
Most computational fluid dynamic (CFD) simulations of aneurysm hemodynamics assume
constant (Newtonian) viscosity, even though blood demonstrates shear-thinning (non …

Wall shear stress association with rupture status in volume matched sidewall aneurysms

A Lauric, J Hippelheuser, AD Cohen… - Journal of …, 2014 - jnis.bmj.com
Objective Flow induced tangential wall shear stress (WSS) is thought to be involved in
aneurysm formation, growth, and rupture. Low WSS was previously associated with rupture …

[HTML][HTML] Longitudinal alterations in cerebral perfusion following a season of adolescent contact sport participation compared to non-contact athletes

BL Brett, AD Cohen, MA McCrea, Y Wang - NeuroImage: Clinical, 2023 - Elsevier
Background Cerebral blood flow (CBF) change, a non-invasive marker of head injury, has
yet to be thoroughly investigated as a potential consequence of repetitive head impacts …

Independent component analysis of dynamic susceptibility contrast MRI in brain tumor: a new biomarker for measuring tumor perfusion patterns

PS LaViolette, AD Cohen, SD Rand… - Proc ISMRM …, 2011 - archive.ismrm.org
It is well known that tumor growth beyond a size of about 2 mm requires the development of
its own blood vessels, a process termed angiogenesis. While physiologic angiogenesis …

ADC-FLAIR Mismatch Excluding Enhancement (AFMEE), a Potential Biomarker of Tumor Invasion

PS LaViolette, AD Cohen, SD Rand, W Mueller… - archive.ismrm.org
The detection of invading brain tumor cells, beyond the traditional contrast-enhancing
regions, continues to be a challenge for the treatment of brain tumors. While areas of FLAIR …

[CITATION][C] Contrast leakage in high grade glioma measured with independent component analysis of dynamic susceptibility contrast MRI

PS LaViolette, AD Cohen… - Proc ISMRM, Melbourne …, 2012 - archive.ismrm.org
This study measures the difference between the two separate contrast agent boluses in
patients with high-grade glioma using regions of interest (ROIs) defined by a novel unbiased …

[CITATION][C] Precise ex-vivo histological validation of heightened cellularity in regions of dark ADC in three cases of high-grade glioma

PS LaViolette, EJ Cochran, AD Cohen… - 20th Annual Meeting …, 2012 - archive.ismrm.org
AFMM (ADC FLAIR MisMatch) is defined as an area of low ADC within FLAIR abnormality
associated with a brain tumor. The aim of this study is to determine if areas of AFMM …

[CITATION][C] ADC-FLAIR MISMATCH EXCLUDING ENHANCEMENT (AFMEE), A POTENTIAL BIOMARKER OF TUMOR INFILTRATION

PS LaViolette, AD Cohen… - NEURO …, 2011 - … DEPT, 2001 EVANS RD, CARY, NC …