A novel human disease with abnormal prion protein sensitive to protease

P Gambetti, Z Dong, J Yuan, X Xiao… - Annals of Neurology …, 2008 - Wiley Online Library
Objective To report a novel prion disease characterized by distinct histopathological and
immunostaining features, and associated with an abnormal isoform of the prion protein (PrP) …

Guillain–Barré syndrome: incidence and mortality rates in US hospitals

A Alshekhlee, Z Hussain, B Sultan, B Katirji - Neurology, 2008 - AAN Enterprises
Objective: To determine the incidence, in-hospital mortality, and predictors of death in
Guillain–Barré syndrome (GBS) in a large US cohort. Methods: Our cohort was identified …

Hospital mortality and complications of electively clipped or coiled unruptured intracranial aneurysm

A Alshekhlee, S Mehta, RC Edgell, N Vora, E Feen… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—To determine the hospital mortality rates associated with elective
surgical clipping and endovascular coiling of unruptured intracranial aneurysms. Methods …

In-hospital mortality of generalized convulsive status epilepticus: a large US sample

M Koubeissi, A Alshekhlee - Neurology, 2007 - AAN Enterprises
Objective: To evaluate the in-hospital mortality associated with generalized convulsive
status epilepticus (GCSE), and predictors of death in a large US cohort. Methods: We …

Mortality of cerebral venous–sinus thrombosis in a large national sample

AB Haghighi, RC Edgell, S Cruz-Flores, E Feen… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—The purpose of this study was to evaluate the mortality rates
associated with cerebral venous–sinus thrombosis in a large national sample. Methods—A …

Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt–Jakob disease: its effect on the phenotype and prion-type characteristics

I Cali, R Castellani, A Alshekhlee, Y Cohen, J Blevins… - Brain, 2009 - academic.oup.com
Five phenotypically distinct subtypes have been identified in sporadic Creutzfeldt–Jakob
disease (sCJD), based on the methionine/valine polymorphic genotype of codon 129 of the …

TREVO stent-retriever mechanical thrombectomy for acute ischemic stroke secondary to large vessel occlusion registry

OO Zaidat, AC Castonguay, RG Nogueira… - Journal of …, 2018 - jnis.bmj.com
AbsTrACT background recent randomized clinical trials (rcTs) demonstrated the efficacy of
mechanical thrombectomy using stent-retrievers in patients with acute ischemic stroke (ais) …

The WOVEN trial: wingspan one-year vascular events and neurologic outcomes

MJ Alexander, A Zauner, R Gupta… - Journal of …, 2021 - jnis.bmj.com
Background Prior studies evaluating the Wingspan stent for treatment of symptomatic
intracranial atherosclerotic disease have included patients with a spectrum of both on-label …

Hypotension unawareness in profound orthostatic hypotension

SD Arbogast, A Alshekhlee, Z Hussain… - The American journal of …, 2009 - Elsevier
BACKGROUND: Clinicians depend on history given by the patients when considering the
diagnosis of orthostatic hypotension. METHODS: Patients with a decrease in systolic blood …

Neuromuscular manifestations of endocrine disorders

A Alshekhlee, HJ Kaminski, RL Ruff - Neurologic clinics, 2002 - neurologic.theclinics.com
Chronic glucocorticoid excess directly causes muscle weakness. Muscle wasting in
Cushing's disease reverses if the glucocorticoid levels are normalized. 105 Patients …