User profiles for "author:Anand Patel"

Anand D. Patel

- Verified email at ucsd.edu - Cited by 5766

Anand G. Patel

- Verified email at alumni.duke.edu - Cited by 4207

Anand C. Patel, MD MS

- Verified email at emdserono.com - Cited by 3489

PARP inhibition: PARP1 and beyond

M Rouleau, A Patel, MJ Hendzel, SH Kaufmann… - Nature reviews …, 2010 - nature.com
Recent findings have thrust poly (ADP-ribose) polymerases (PARPs) into the limelight as
potential chemotherapeutic targets. To provide a framework for understanding these recent …

[HTML][HTML] Nanotechnology in wastewater management: a new paradigm towards wastewater treatment

K Jain, AS Patel, VP Pardhi, SJS Flora - Molecules, 2021 - mdpi.com
Clean and safe water is a fundamental human need for multi-faceted development of society
and a thriving economy. Brisk rises in populations, expanding industrialization, urbanization …

Talimogene laherparepvec (T-VEC) and other oncolytic viruses for the treatment of melanoma

PK Bommareddy, A Patel, S Hossain… - American journal of …, 2017 - Springer
Many mammalian viruses have properties that can be commandeered for the treatment of
cancer. These characteristics include preferential infection and replication in tumor cells, the …

Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease

EY Kim, JT Battaile, AC Patel, Y You, E Agapov… - Nature medicine, 2008 - nature.com
To understand the pathogenesis of chronic inflammatory disease, we analyzed an
experimental mouse model of chronic lung disease with pathology that resembles asthma …

Nonhomologous end joining drives poly (ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells

AG Patel, JN Sarkaria… - Proceedings of the …, 2011 - National Acad Sciences
Poly (ADP-ribose) polymerase (PARP) inhibitors are strikingly toxic to cells with defects in
homologous recombination (HR). The mechanistic basis for these findings is incompletely …

The utility of CA 19-9 in the diagnoses of cholangiocarcinoma in patients without primary sclerosing cholangitis

AH Patel, DM Harnois, GG Klee, NF LaRusso… - The American journal of …, 2000 - Elsevier
OBJECTIVES: The diagnosis of cholangiocarcinoma is often difficult, making management
approaches problematic. A reliable serum tumor marker for cholangiocarcinoma would be a …

Marine bacterial, archaeal and protistan association networks reveal ecological linkages

JA Steele, PD Countway, L Xia, PD Vigil… - The ISME …, 2011 - academic.oup.com
Microbes have central roles in ocean food webs and global biogeochemical processes, yet
specific ecological relationships among these taxa are largely unknown. This is in part due …

[HTML][HTML] A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

M Slyper, CBM Porter, O Ashenberg, J Waldman… - Nature medicine, 2020 - nature.com
Single-cell genomics is essential to chart tumor ecosystems. Although single-cell RNA-Seq
(scRNA-Seq) profiles RNA from cells dissociated from fresh tumors, single-nucleus RNA …

Temperature triggered self-assembly of polypeptides into multivalent spherical micelles

MR Dreher, AJ Simnick, K Fischer… - Journal of the …, 2008 - ACS Publications
We report herein thermally responsive elastin-like polypeptides (ELPs) in a linear AB diblock
architecture with an N-terminal peptide ligand that self-assemble into spherical micelles …

[HTML][HTML] Long-term IL-33–producing epithelial progenitor cells in chronic obstructive lung disease

DE Byers, J Alexander-Brett, AC Patel… - The Journal of …, 2013 - Am Soc Clin Investig
Chronic obstructive lung disease is characterized by persistent abnormalities in epithelial
and immune cell function that are driven, at least in part, by infection. Analysis of …