User profiles for "author:Benjamin Pulli"
Benjamin Pulli, MDMassachusetts General Hospital & Harvard Medical School Verified email at mgh.harvard.edu Cited by 2328 |
Myeloperoxidase inhibition improves ventricular function and remodeling after experimental myocardial infarction
PF-1355 is an oral myeloperoxidase (MPO) inhibitor that successfully decreased elevated
MPO activity in mouse myocardial infarction models. Short duration PF-1355 treatment for 7 …
MPO activity in mouse myocardial infarction models. Short duration PF-1355 treatment for 7 …
Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model
INTRODUCTION Alzheimer's disease (AD) is the most common form of age-related
dementia, characterized by cognitive impairment, neurodegeneration, β-amyloid (Aβ) …
dementia, characterized by cognitive impairment, neurodegeneration, β-amyloid (Aβ) …
[HTML][HTML] Measuring myeloperoxidase activity in biological samples
Background Enzymatic activity measurements of the highly oxidative enzyme
myeloperoxidase (MPO), which is implicated in many diseases, are widely used in the …
myeloperoxidase (MPO), which is implicated in many diseases, are widely used in the …
Imaging-based treatment selection for intravenous and intra-arterial stroke therapies: a comprehensive review
AJ Yoo, B Pulli, RG Gonzalez - Expert review of cardiovascular …, 2011 - Taylor & Francis
Reperfusion therapy is the only approved treatment for acute ischemic stroke. The current
approach to patient selection is primarily based on the time from stroke symptom onset …
approach to patient selection is primarily based on the time from stroke symptom onset …
[HTML][HTML] Imaging neuroinflammation–from bench to bedside
Neuroinflammation plays a central role in a variety of neurological diseases, including
stroke, multiple sclerosis, Alzheimer's disease, and malignant CNS neoplasms, among …
stroke, multiple sclerosis, Alzheimer's disease, and malignant CNS neoplasms, among …
Myeloperoxidase–hepatocyte–stellate cell cross talk promotes hepatocyte injury and fibrosis in experimental nonalcoholic steatohepatitis
Abstract Aims: Myeloperoxidase (MPO), a highly oxidative enzyme secreted by leukocytes
has been implicated in human and experimental nonalcoholic steatohepatitis (NASH), but …
has been implicated in human and experimental nonalcoholic steatohepatitis (NASH), but …
Demyelinating diseases: myeloperoxidase as an imaging biomarker and therapeutic target
R Forghani, GR Wojtkiewicz, Y Zhang, D Seeburg… - Radiology, 2012 - pubs.rsna.org
Purpose To evaluate myeloperoxidase (MPO) as a newer therapeutic target and bis-5-
hydroxytryptamide-diethylenetriaminepentaacetate-gadolinium (Gd)(MPO-Gd) as an …
hydroxytryptamide-diethylenetriaminepentaacetate-gadolinium (Gd)(MPO-Gd) as an …
Acute ischemic stroke: infarct core estimation on CT angiography source images depends on CT angiography protocol
B Pulli, PW Schaefer, R Hakimelahi, ZA Chaudhry… - Radiology, 2012 - pubs.rsna.org
Purpose To test whether the relationship between acute ischemic infarct size on concurrent
computed tomographic (CT) angiography source images and diffusion-weighted (DW) …
computed tomographic (CT) angiography source images and diffusion-weighted (DW) …
Mouse model of anti-NMDA receptor post–herpes simplex encephalitis
J Linnoila, B Pulli, T Armangué… - Neurology …, 2018 - AAN Enterprises
Objective To develop an endogenous rodent model of postinfectious anti-NMDA receptor
(NMDAR) encephalitis. Methods Six mice were inoculated intranasally with herpes simplex …
(NMDAR) encephalitis. Methods Six mice were inoculated intranasally with herpes simplex …
Theranostic nanoparticles based on bioreducible polyethylenimine-coated iron oxide for reduction-responsive gene delivery and magnetic resonance imaging
Theranostic nanoparticles based on superparamagnetic iron oxide (SPIO) have a great
promise for tumor diagnosis and gene therapy. However, the availability of theranostic …
promise for tumor diagnosis and gene therapy. However, the availability of theranostic …