Neuronal subtype specification in the cerebral cortex
BJ Molyneaux, P Arlotta, JRL Menezes… - Nature reviews …, 2007 - nature.com
In recent years, tremendous progress has been made in understanding the mechanisms
underlying the specification of projection neurons within the mammalian neocortex. New …
underlying the specification of projection neurons within the mammalian neocortex. New …
[PDF][PDF] Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo
P Arlotta, BJ Molyneaux, J Chen, J Inoue, R Kominami… - Neuron, 2005 - cell.com
Within the vertebrate nervous system, the presence of many different lineages of neurons
and glia complicates the molecular characterization of single neuronal populations. In order …
and glia complicates the molecular characterization of single neuronal populations. In order …
[HTML][HTML] Fezl is required for the birth and specification of corticospinal motor neurons
The molecular mechanisms controlling the differentiation of neural progenitors into distinct
subtypes of neurons during neocortical development are unknown. Here, we report that Fezl …
subtypes of neurons during neocortical development are unknown. Here, we report that Fezl …
[HTML][HTML] SOX5 controls the sequential generation of distinct corticofugal neuron subtypes
The molecular mechanisms controlling the development of distinct subtypes of neocortical
projection neurons, and CNS neuronal diversity more broadly, are only now emerging. We …
projection neurons, and CNS neuronal diversity more broadly, are only now emerging. We …
Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum
P Arlotta, BJ Molyneaux, D Jabaudon… - Journal of …, 2008 - Soc Neuroscience
Striatal medium spiny neurons (MSN) are critically involved in motor control, and their
degeneration is a principal component of Huntington's disease. We find that the transcription …
degeneration is a principal component of Huntington's disease. We find that the transcription …
Care of the post-thrombectomy patient
Catheter-based angiography is typically performed via the transfemoral approach; however,
this route may not be feasible in patients with severe femoral, external iliac, or aortic disease …
this route may not be feasible in patients with severe femoral, external iliac, or aortic disease …
[PDF][PDF] DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex
BJ Molyneaux, LA Goff, AC Brettler, HH Chen… - Neuron, 2015 - cell.com
Neuronal development requires a complex choreography of transcriptional decisions to
obtain specific cellular identities. Realizing the ultimate goal of identifying genome-wide …
obtain specific cellular identities. Realizing the ultimate goal of identifying genome-wide …
Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons
BJ Molyneaux, P Arlotta, RM Fame… - Journal of …, 2009 - Soc Neuroscience
Little is known about the molecular development and heterogeneity of callosal projection
neurons (CPN), cortical commissural neurons that connect homotopic regions of the two …
neurons (CPN), cortical commissural neurons that connect homotopic regions of the two …
Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 …
Background Preclinical models of stroke have shown that intravenous glyburide reduces
brain swelling and improves survival. We assessed whether intravenous glyburide (RP …
brain swelling and improves survival. We assessed whether intravenous glyburide (RP …
Transport of ER vesicles on actin filaments in neurons by myosin V
JS Tabb, BJ Molyneaux, DL Cohen… - Journal of cell …, 1998 - journals.biologists.com
Axoplasmic organelles in the giant axon of the squid have been shown to move on both
actin filaments and microtubules and to switch between actin filaments and microtubules …
actin filaments and microtubules and to switch between actin filaments and microtubules …