Neuronal subtype specification in the cerebral cortex

BJ Molyneaux, P Arlotta, JRL Menezes… - Nature reviews …, 2007 - nature.com
In recent years, tremendous progress has been made in understanding the mechanisms
underlying the specification of projection neurons within the mammalian neocortex. New …

[PDF][PDF] Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo

P Arlotta, BJ Molyneaux, J Chen, J Inoue, R Kominami… - Neuron, 2005 - cell.com
Within the vertebrate nervous system, the presence of many different lineages of neurons
and glia complicates the molecular characterization of single neuronal populations. In order …

[HTML][HTML] Fezl is required for the birth and specification of corticospinal motor neurons

BJ Molyneaux, P Arlotta, T Hirata, M Hibi, JD Macklis - Neuron, 2005 - cell.com
The molecular mechanisms controlling the differentiation of neural progenitors into distinct
subtypes of neurons during neocortical development are unknown. Here, we report that Fezl …

[HTML][HTML] SOX5 controls the sequential generation of distinct corticofugal neuron subtypes

T Lai, D Jabaudon, BJ Molyneaux, E Azim, P Arlotta… - Neuron, 2008 - cell.com
The molecular mechanisms controlling the development of distinct subtypes of neocortical
projection neurons, and CNS neuronal diversity more broadly, are only now emerging. We …

Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum

P Arlotta, BJ Molyneaux, D Jabaudon… - Journal of …, 2008 - Soc Neuroscience
Striatal medium spiny neurons (MSN) are critically involved in motor control, and their
degeneration is a principal component of Huntington's disease. We find that the transcription …

Care of the post-thrombectomy patient

AP Jadhav, BJ Molyneaux, MD Hill, TG Jovin - Stroke, 2018 - Am Heart Assoc
Catheter-based angiography is typically performed via the transfemoral approach; however,
this route may not be feasible in patients with severe femoral, external iliac, or aortic disease …

[PDF][PDF] DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex

BJ Molyneaux, LA Goff, AC Brettler, HH Chen… - Neuron, 2015 - cell.com
Neuronal development requires a complex choreography of transcriptional decisions to
obtain specific cellular identities. Realizing the ultimate goal of identifying genome-wide …

Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons

BJ Molyneaux, P Arlotta, RM Fame… - Journal of …, 2009 - Soc Neuroscience
Little is known about the molecular development and heterogeneity of callosal projection
neurons (CPN), cortical commissural neurons that connect homotopic regions of the two …

Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 …

KN Sheth, JJ Elm, BJ Molyneaux, H Hinson… - The Lancet …, 2016 - thelancet.com
Background Preclinical models of stroke have shown that intravenous glyburide reduces
brain swelling and improves survival. We assessed whether intravenous glyburide (RP …

Transport of ER vesicles on actin filaments in neurons by myosin V

JS Tabb, BJ Molyneaux, DL Cohen… - Journal of cell …, 1998 - journals.biologists.com
Axoplasmic organelles in the giant axon of the squid have been shown to move on both
actin filaments and microtubules and to switch between actin filaments and microtubules …