[HTML][HTML] An introduction to spatial transcriptomics for biomedical research

CG Williams, HJ Lee, T Asatsuma, R Vento-Tormo… - Genome Medicine, 2022 - Springer
Single-cell transcriptomics (scRNA-seq) has become essential for biomedical research over
the past decade, particularly in developmental biology, cancer, immunology, and …

Extending thrombolysis to 4· 5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data

BCV Campbell, H Ma, PA Ringleb, MW Parsons… - The Lancet, 2019 - thelancet.com
Background Stroke thrombolysis with alteplase is currently recommended 0–4· 5 h after
stroke onset. We aimed to determine whether perfusion imaging can identify patients with …

Hands on what? The relative effectiveness of physical versus virtual materials in an engineering design project by middle school children

D Klahr, LM Triona, C Williams - Journal of Research in Science …, 2007 - Wiley Online Library
Abstract “Hands‐on” activities play an important, but controversial, role in early science
education. In this study we attempt to clarify some of the issues surrounding the controversy …

Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4· 5 H of stroke onset: an open-label, blinded-endpoint …

PJ Mitchell, B Yan, L Churilov, RJ Dowling, SJ Bush… - The Lancet, 2022 - thelancet.com
Background The benefit of combined treatment with intravenous thrombolysis before
endovascular thrombectomy in patients with acute ischaemic stroke caused by large vessel …

Population of anatomically variable 4D XCAT adult phantoms for imaging research and optimization

WP Segars, J Bond, J Frush, S Hon… - Medical …, 2013 - Wiley Online Library
Purpose: The authors previously developed the 4D extended cardiac‐torso (XCAT) phantom
for multimodality imaging research. The XCAT consisted of highly detailed whole‐body …

Effect of intravenous tenecteplase dose on cerebral reperfusion before thrombectomy in patients with large vessel occlusion ischemic stroke: the EXTEND-IA TNK part …

BCV Campbell, PJ Mitchell, L Churilov, N Yassi… - Jama, 2020 - jamanetwork.com
Importance Intravenous thrombolysis with tenecteplase improves reperfusion prior to
endovascular thrombectomy for ischemic stroke compared with alteplase. Objective To …

Channels and valley networks.

VR Baker, MH Carr, VC Gulick, CR Williams… - Mars, 1992 - ui.adsabs.harvard.edu
Attention is given to Martian channels and valley networks, since they have become a
principal element of evidence to the effect that the Martian atmosphere evolved from an early …

[HTML][HTML] Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first in-human …

TJ Oxley, PE Yoo, GS Rind, SM Ronayne… - Journal of …, 2021 - jnis.bmj.com
Background Implantable brain–computer interfaces (BCIs), functioning as motor
neuroprostheses, have the potential to restore voluntary motor impulses to control digital …

Investigating the impact of polymer functional groups on the stability and activity of lysozyme–polymer conjugates

M Lucius, R Falatach, C McGlone, K Makaroff… - …, 2016 - ACS Publications
Polymers are often conjugated to proteins to improve stability; however, the impact of
polymer chain length and functional groups on protein structure and function is not well …

[HTML][HTML] The Cdc48 unfoldase prepares well-folded protein substrates for degradation by the 26S proteasome

MM Olszewski, C Williams, KC Dong… - Communications …, 2019 - nature.com
Cdc48/p97 is an essential and highly conserved AAA+ ATPase that uses its protein-
unfoldase activity to extract ubiquitinated polypeptides from macromolecular complexes and …