Physical factors effecting cerebral aneurysm pathophysiology

C Sadasivan, DJ Fiorella, HH Woo… - Annals of biomedical …, 2013 - Springer
Many factors that are either blood-, wall-, or hemodynamics-borne have been associated
with the initiation, growth, and rupture of intracranial aneurysms. The distribution of cerebral …

Endoluminal scaffolds for vascular reconstruction and exclusion of aneurysms from the cerebral circulation

BB Lieber, C Sadasivan - Stroke, 2010 - Am Heart Assoc
The latest class of neuroendovascular devices being evaluated is intended to treat cerebral
aneurysms. In addition to inducing flow stasis–mediated thrombosis of aneurysms and thus …

An original flow diversion device for the treatment of intracranial aneurysms: evaluation in the rabbit elastase-induced model

C Sadasivan, L Cesar, J Seong, A Rakian, Q Hao… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—The potential for successful treatment of intracranial aneurysms
by flow diversion is gradually being recognized in the clinical setting; however, the devices …

Hemodynamics of flow diverters

R Dholakia, C Sadasivan… - Journal of …, 2017 - asmedigitalcollection.asme.org
Cerebral aneurysms are pathological focal evaginations of the arterial wall at and around
the junctions of the circle of Willis. Their tenuous walls predispose aneurysms to leak or …

Modeling the interaction of coils with the local blood flow after coil embolization of intracranial aneurysms

KS Cha, E Balaras, BB Lieber… - Journal of …, 2007 - asmedigitalcollection.asme.org
Aneurysmal recanalization and coil compaction after coil embolization of intracranial
aneurysms are seen in as many as 40% of cases. Higher packing density has been …

Treatment of rabbit elastase-induced aneurysm models by flow diverters: development of quantifiable indexes of device performance using digital subtraction …

C Sadasivan, L Cesar, J Seong… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
It has been known for more than a decade that intracranial aneurysms can be successfully
treated by deploying a porous meshed tube in the parent vessel of the aneurysm. Such …

Hemodynamics of carotid artery atherosclerotic occlusive disease

AK Wakhloo, BB Lieber, J Seong, C Sadasivan… - Journal of Vascular and …, 2004 - Elsevier
Hemodynamic mechanisms for the initiation and progression of carotid bifurcation
atherosclerotic occlusive disease have been extensively researched during the past few …

Angiographic quantification of contrast medium washout from cerebral aneurysms after stent placement

C Sadasivan, BB Lieber, MJ Gounis… - American journal …, 2002 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Endovascular stent placement is an emerging technique
in treating cerebral aneurysms. Thus far, no quantitative method is available to determine …

The mixability of angiographic contrast with arterial blood

BB Lieber, C Sadasivan, Q Hao, J Seong… - Medical …, 2009 - Wiley Online Library
Purpose: Angiographic contrast that is routinely injected into arteries is used not only to
evaluate arterial geometry but also in many cases to assess perfusion. The authors …

Correlation between angiographic and particle image velocimetry quantifications of flow diverters in an in vitro model of elastase-induced rabbit aneurysms

AL Trager, C Sadasivan, J Seong, BB Lieber - 2009 - asmedigitalcollection.asme.org
The rupture of a cerebral aneurysm can result in a hemorrhagic stroke. A flow diverter, which
is a porous tubular mesh, can be placed across the neck of a cerebral aneurysm to induce …