User profiles for "author:Christopher MacIsaac"

Christopher MacIsaac

Asoociate Professor Intensive Care
Verified email at mh.org.au
Cited by 3033

Prognostic accuracy of the SOFA score, SIRS criteria, and qSOFA score for in-hospital mortality among adults with suspected infection admitted to the intensive care …

EP Raith, AA Udy, M Bailey, S McGloughlin… - Jama, 2017 - jamanetwork.com
Importance The Sepsis-3 Criteria emphasized the value of a change of 2 or more points in
the Sequential [Sepsis-related] Organ Failure Assessment (SOFA) score, introduced quick …

[HTML][HTML] Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first in-human …

TJ Oxley, PE Yoo, GS Rind, SM Ronayne… - Journal of …, 2021 - jnis.bmj.com
Background Implantable brain–computer interfaces (BCIs), functioning as motor
neuroprostheses, have the potential to restore voluntary motor impulses to control digital …

Epidemiology of sepsis in Victoria, Australia

V Sundararajan, CM MacIsaac, JJ Presneill… - Critical care …, 2005 - journals.lww.com
Objective: To determine the clinical and epidemiologic characteristics of patients with sepsis
admitted to hospitals in Victoria, Australia, including the incidence of sepsis and severe …

[HTML][HTML] The Melbourne epidemic thunderstorm asthma event 2016: an investigation of environmental triggers, effect on health services, and patient risk factors

F Thien, PJ Beggs, D Csutoros, J Darvall… - The Lancet Planetary …, 2018 - thelancet.com
Background A multidisciplinary collaboration investigated the world's largest, most
catastrophic epidemic thunderstorm asthma event that took place in Melbourne, Australia …

Targeted full energy and protein delivery in critically ill patients: a pilot randomized controlled trial (FEED trial)

K Fetterplace, AM Deane, A Tierney… - Journal of Parenteral …, 2018 - Wiley Online Library
Background International guidelines recommend greater protein delivery to critically ill
patients than they currently receive. This pilot randomized clinical trial aimed to determine …

The incidence of acute kidney injury in patients with traumatic brain injury

EM Moore, R Bellomo, A Nichol, N Harley… - Renal failure, 2010 - Taylor & Francis
There is limited information on the incidence of acute kidney injury (AKI) in patients with
traumatic brain injury (TBI) although AKI may contribute to morbidity and mortality. We …

Systematic review with meta‐analysis of patient‐centered outcomes, comparing international guideline–recommended enteral protein delivery with usual care

K Fetterplace, BMT Gill, LS Chapple… - Journal of Parenteral …, 2020 - Wiley Online Library
Background International guidelines recommend that protein be administered enterally to
critically ill patients at doses between 1.2 and 2 g/kg per day Observational data indicate that …

Assessment of safety of a fully implanted endovascular brain-computer interface for severe paralysis in 4 patients: the stentrode with thought-controlled digital switch …

P Mitchell, SCM Lee, PE Yoo, A Morokoff… - JAMA …, 2023 - jamanetwork.com
Importance Brain-computer interface (BCI) implants have previously required craniotomy to
deliver penetrating or surface electrodes to the brain. Whether a minimally invasive …

Nebulised heparin for patients with or at risk of acute respiratory distress syndrome: a multicentre, randomised, double-blind, placebo-controlled phase 3 trial

B Dixon, RJ Smith, DJ Campbell, JL Moran… - The Lancet …, 2021 - thelancet.com
Background Mechanical ventilation in intensive care for 48 h or longer is associated with the
acute respiratory distress syndrome (ARDS), which might be present at the time ventilatory …

[PDF][PDF] A hospital‐wide response to multiple outbreaks of COVID‐19 in health care workers: lessons learned from the field

KL Buising, D Williamson, BC Cowie… - The Medical Journal of …, 2021 - mja.com.au
Setting The Royal Melbourne Hospital City Campus is a 550-bed university-affiliated tertiary
hospital with an additional 150 geriatric and rehabilitation beds at the Royal Park Campus, a …