Poly (vinylpyridine)-containing block copolymers for smart, multicompartment particles

D Lee, J Kim, KH Ku, S Li, JJ Shin, BJ Kim - Polymer Chemistry, 2022 - pubs.rsc.org
Multicompartment particles generated by the self-assembly of block copolymers (BCPs)
have received considerable attention due to their unique morphologies and functionalities. A …

[PDF][PDF] Magnesium sensing via LFA-1 regulates CD8+ T cell effector function

J Lötscher, AAM i Líndez, N Kirchhammer, E Cribioli… - Cell, 2022 - cell.com
The relevance of extracellular magnesium in cellular immunity remains largely unknown.
Here, we show that the co-stimulatory cell-surface molecule LFA-1 requires magnesium to …

[HTML][HTML] Scientific validation and clinical application of lung cancer organoids

D Lee, Y Kim, C Chung - Cells, 2021 - mdpi.com
Lung cancer organoid (LCO) is a novel model of lung cancer that facilitates drug screening.
However, the success rate of LCOs varies from 7% to 87%, and the culture medium …

[HTML][HTML] Leaky gum: the revisited origin of systemic diseases

DY Park, JY Park, D Lee, I Hwang, HS Kim - Cells, 2022 - mdpi.com
The oral cavity is the gateway for microorganisms into your body where they disseminate not
only to the directly connected respiratory and digestive tracts but also to the many remote …

Hippo pathway effector YAP inhibition restores the sensitivity of EGFR-TKI in lung adenocarcinoma having primary or acquired EGFR-TKI resistance

JE Lee, HS Park, D Lee, G Yoo, T Kim, H Jeon… - Biochemical and …, 2016 - Elsevier
The efficacy of EGFR-tyrosine kinase inhibitors (TKIs) is significantly limited by various
resistance mechanisms to those drugs. The resistance to EGFR-TKI is largely divided by two …

MRTF potentiates TEAD‐YAP transcriptional activity causing metastasis

T Kim, D Hwang, D Lee, JH Kim, SY Kim… - The EMBO Journal, 2017 - embopress.org
Yes‐associated protein (YAP) and myocardin‐related transcription factor (MRTF) play
similar roles and exhibit significant crosstalk in directing transcriptional responses to …

Sharkskin-mimetic desalination membranes with ultralow biofouling

W Choi, C Lee, D Lee, YJ Won, GW Lee… - Journal of materials …, 2018 - pubs.rsc.org
Biofouling is a pervasive problem for any materials that are exposed to aquatic
environments. Especially, it is a dire problem for the desalination membranes used to …

[HTML][HTML] Cryobiopsy: a breakthrough strategy for clinical utilization of lung cancer organoids

D Park, D Lee, Y Kim, Y Park, YJ Lee, JE Lee, MK Yeo… - Cells, 2023 - mdpi.com
One major challenge associated with lung cancer organoids (LCOs) is their predominant
derivation from surgical specimens of patients with early-stage lung cancer. However …

Totally implantable enzymatic biofuel cell and brain stimulator operating in bird through wireless communication

D Lee, SH Jeong, S Yun, S Kim, J Sung, J Seo… - Biosensors and …, 2021 - Elsevier
Animals digest food to fuel brain neurometabolism via cellular respiration. This study
demonstrates the combination of a biofuel cell (BFC) and an animal brain stimulator (ABS) …

YAP and AP-1 cooperate to initiate pancreatic cancer development from ductal cells in mice

J Park, D Eisenbarth, W Choi, H Kim, C Choi, D Lee… - Cancer research, 2020 - AACR
The development of pancreatic cancer is heavily dependent upon the aberrant activation of
KRAS signaling. Among the downstream targets of KRAS, the effectors of the Hippo pathway …