Importance Tirofiban is a highly selective nonpeptide antagonist of glycoprotein IIb/IIIa
receptor, which reversibly inhibits platelet aggregation. It remains uncertain whether …

Importance Endovascular therapy (EVT) demonstrated better outcomes compared with
medical management in recent randomized clinical trials (RCTs) of patients with large …

Two recently published JNIS commentaries1 2 on eligibility criteria for the clinical trials on
patients with large core, acute ischemic stroke (AIS) with large vessel occlusion have …

Importance It is uncertain whether intravenous methylprednisolone improves outcomes for
patients with acute ischemic stroke due to large-vessel occlusion (LVO) undergoing …

Background Endovascular therapy (EVT) was demonstrated effective in acute large vessel
occlusion (LVO) with large infarction. Revealing subgroups of patients who would or would …

Background The aim of this study was to explore epilepsy-related mechanism so as to figure
out the possible targets for epilepsy treatment. Methods The gene expression profile dataset …

Background Approximately half of patients who achieve successful reperfusion do not
achieve functional independence. The present study sought to investigate the clinical …

Importance It is uncertain whether intravenous methylprednisolone improves outcomes for
patients with acute ischemic stroke due to large-vessel occlusion (LVO) undergoing …

Background A link between body temperature and stroke outcomes has been established
but not for acute basilar artery occlusion. We aimed to determine the association between …

Background: Edaravone dexborneol has been confirmed as a novel neuroprotective agent
by acting on multiple active targets of antioxidation and anti-inflammation. Objectives: This …