Honoring 50 Years of Clinical Heart Transplantation in Circulation In-Depth State-of-the-Art Review

J Stehlik, J Kobashigawa, SA Hunt, H Reichenspurner… - Circulation, 2018 - Am Heart Assoc
Heart transplantation has become a standard therapy option for advanced heart failure. The
translation of heart transplantation from innovative experiments to long-term clinical success …

The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation

P Menasché, O Alfieri, S Janssens, W McKenna… - Circulation, 2008 - Am Heart Assoc
Background—Phase I clinical studies have demonstrated the feasibility of implanting
autologous skeletal myoblasts in postinfarction scars. However, they have failed to …

Vascular wall resident progenitor cells: a source for postnatal vasculogenesis

E Zengin, F Chalajour, UM Gehling, WD Ito, H Treede… - 2006 - journals.biologists.com
Here, we report the existence of endothelial precursor (EPC) and stem cells in a distinct
zone of the vascular wall that are capable to differentiate into mature endothelial cells …

Left ventricular unloading is associated with lower mortality in patients with cardiogenic shock treated with venoarterial extracorporeal membrane oxygenation: results …

B Schrage, PM Becher, A Bernhardt, H Bezerra… - Circulation, 2020 - Am Heart Assoc
Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is
increasingly used to treat cardiogenic shock. However, VA-ECMO might hamper myocardial …

Report from a consensus conference on primary graft dysfunction after cardiac transplantation

J Kobashigawa, A Zuckermann, P Macdonald… - The Journal of Heart and …, 2014 - Elsevier
Although primary graft dysfunction (PGD) is fairly common early after cardiac transplant,
standardized schemes for diagnosis and treatment remain contentious. Most major cardiac …

Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the …

DJFM Thuijs, AP Kappetein, PW Serruys, FW Mohr… - The Lancet, 2019 - thelancet.com
Summary Background The Synergy between PCI with Taxus and Cardiac Surgery
(SYNTAX) trial was a non-inferiority trial that compared percutaneous coronary intervention …

Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients

T Deuse, X Hu, A Gravina, D Wang, G Tediashvili… - Nature …, 2019 - nature.com
Autologous induced pluripotent stem cells (iPSCs) constitute an unlimited cell source for
patient-specific cell-based organ repair strategies. However, their generation and …

Concomitant implantation of Impella® on top of veno‐arterial extracorporeal membrane oxygenation may improve survival of patients with cardiogenic shock

F Pappalardo, C Schulte, M Pieri… - European journal of …, 2017 - Wiley Online Library
Aims Veno‐arterial extracorporeal membrane oxygenation (VA‐ECMO) support stabilizes
patients with cardiogenic shock. Despite improved oxygenation and peripheral circulation …

Acute outcomes of MitraClip therapy for mitral regurgitation in high-surgical-risk patients: emphasis on adverse valve morphology and severe left ventricular …

O Franzen, S Baldus, V Rudolph, S Meyer… - European heart …, 2010 - academic.oup.com
Aims We sought to assess the feasibility of catheter-based mitral valve repair using the
MitraClip system in high-surgical-risk patients with mitral regurgitation (MR)≥ grade 3+ …

Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation

V Rudolph, RP Andrié, TK Rudolph, K Friedrichs… - Nature medicine, 2010 - nature.com
Observational clinical and ex vivo studies have established a strong association between
atrial fibrillation and inflammation. However, whether inflammation is the cause or the …