Extending thrombolysis to 4· 5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data

BCV Campbell, H Ma, PA Ringleb, MW Parsons… - The Lancet, 2019 - thelancet.com
Background Stroke thrombolysis with alteplase is currently recommended 0–4· 5 h after
stroke onset. We aimed to determine whether perfusion imaging can identify patients with …

Association of general anesthesia vs procedural sedation with functional outcome among patients with acute ischemic stroke undergoing thrombectomy: a systematic …

S Schönenberger, PL Hendén, CZ Simonsen… - Jama, 2019 - jamanetwork.com
Importance General anesthesia during thrombectomy for acute ischemic stroke has been
associated with poor neurological outcome in nonrandomized studies. Three single-center …

[HTML][HTML] Computer-aided imaging analysis in acute ischemic stroke–background and clinical applications

Y Mokli, J Pfaff, DP Dos Santos, C Herweh… - … research and practice, 2019 - Springer
Tools for medical image analysis have been developed to reduce the time needed to detect
abnormalities and to provide more accurate results. Particularly, tools based on artificial …

Effect of conscious sedation vs general anesthesia on early neurological improvement among patients with ischemic stroke undergoing endovascular thrombectomy …

S Schönenberger, L Uhlmann, W Hacke, S Schieber… - Jama, 2016 - jamanetwork.com
Importance Optimal management of sedation and airway during thrombectomy for acute
ischemic stroke is controversial due to lack of evidence from randomized trials. Objective To …

Multimodal predictive modeling of endovascular treatment outcome for acute ischemic stroke using machine-learning

G Brugnara, U Neuberger, MA Mahmutoglu, M Foltyn… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: This study assessed the predictive performance and relative
importance of clinical, multimodal imaging, and angiographic characteristics for predicting …

Prevention of adverse drug reactions in intensive care patients by personal intervention based on an electronic clinical decision support system

T Bertsche, J Pfaff, P Schiller, J Kaltschmidt… - Intensive care …, 2010 - Springer
Objective We investigated the effect of written drug information for senior clinicians on the
incidence of drug–drug interactions (DDIs) and DDI-related adverse events in intensive care …

Sedation vs. Intubation for Endovascular Stroke TreAtment (SIESTA)–a randomized monocentric trial

S Schönenberger, M Möhlenbruch… - … Journal of Stroke, 2015 - journals.sagepub.com
Background The optimal peri-interventional management of sedation and airway for
endovascular stroke treatment (EST) appears to be a crucial factor for treatment success …

Classification of bleeding events: comparison of ECASS III (European Cooperative Acute Stroke Study) and the new Heidelberg bleeding classification

U Neuberger, MA Möhlenbruch, C Herweh, C Ulfert… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Intracranial hemorrhage (ICH) after acute ischemic stroke
treatments represents a feared complication with possible prognostic implications. In recent …

Risk factors of intracranial hemorrhage after mechanical thrombectomy of anterior circulation ischemic stroke

U Neuberger, P Kickingereder, S Schönenberger… - Neuroradiology, 2019 - Springer
Purpose Intracranial hemorrhage (ICH) is a potentially severe complication after mechanical
thrombectomy (MT). Here, we investigated risk factors for the occurrence of any and …

e-ASPECTS correlates with and is predictive of outcome after mechanical thrombectomy

J Pfaff, C Herweh, S Schieber… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The e-ASPECTS software is a tool for the automated use
of ASPECTS. Our aim was to analyze whether baseline e-ASPECT scores correlate with …