User profiles for "author:Juhana Frösen"
 | Juhana FrösenProfessor and Chair of Neurosurgery, University of Tampere and Tampere University … Verified email at tuni.fi Cited by 5456 |
Saccular intracranial aneurysm: pathology and mechanisms
J Frösen, R Tulamo, A Paetau, E Laaksamo… - Acta …, 2012 - Springer
Saccular intracranial aneurysms (sIA) are pouch-like pathological dilatations of intracranial
arteries that develop when the cerebral artery wall becomes too weak to resist …
arteries that develop when the cerebral artery wall becomes too weak to resist …
Flow-induced, inflammation-mediated arterial wall remodeling in the formation and progression of intracranial aneurysms
OBJECTIVE Unruptured intracranial aneurysms (UIAs) are relatively common lesions that
may cause devastating intracranial hemorrhage, thus producing considerable suffering and …
may cause devastating intracranial hemorrhage, thus producing considerable suffering and …
Inflammatory changes in the aneurysm wall: a review
R Tulamo, J Frösen, J Hernesniemi… - Journal of …, 2018 - jnis.bmj.com
Rupture of a saccular intracranial artery aneurysm (IA) causes subarachnoid hemorrhage, a
significant cause of stroke and death. The current treatment options, endovascular coiling …
significant cause of stroke and death. The current treatment options, endovascular coiling …
Remodeling of saccular cerebral artery aneurysm wall is associated with rupture: histological analysis of 24 unruptured and 42 ruptured cases
J Frösen, A Piippo, A Paetau, M Kangasniemi… - Stroke, 2004 - Am Heart Assoc
Background and Purpose—The cellular mechanisms of degeneration and repair preceding
rupture of the saccular cerebral artery aneurysm wall need to be elucidated for rational …
rupture of the saccular cerebral artery aneurysm wall need to be elucidated for rational …
[HTML][HTML] Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain
SI Nikolaev, S Vetiska, X Bonilla… - … England Journal of …, 2018 - Mass Medical Soc
Background Sporadic arteriovenous malformations of the brain, which are morphologically
abnormal connections between arteries and veins in the brain vasculature, are a leading …
abnormal connections between arteries and veins in the brain vasculature, are a leading …
Irregular shape of intracranial aneurysm indicates rupture risk irrespective of size in a population-based cohort
AE Lindgren, T Koivisto, J Björkman… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Size and shape of saccular intracranial aneurysms (sIA) reflect
the condition of the sIA wall and were risk factors for rupture in previous follow-up studies …
the condition of the sIA wall and were risk factors for rupture in previous follow-up studies …
Complement activation associates with saccular cerebral artery aneurysm wall degeneration and rupture
R Tulamo, J Frösen, S Junnikkala, A Paetau… - …, 2006 - journals.lww.com
OBJECTIVE: Saccular cerebral artery aneurysm (SCAA) wall degeneration and
inflammatory cell infiltrations associate with aneurysm rupture and subarachnoid …
inflammatory cell infiltrations associate with aneurysm rupture and subarachnoid …
Flow conditions in the intracranial aneurysm lumen are associated with inflammation and degenerative changes of the aneurysm wall
J Cebral, E Ollikainen, BJ Chung… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Saccular intracranial aneurysm is a common disease that
may cause devastating intracranial hemorrhage. Hemodynamics, wall remodeling, and wall …
may cause devastating intracranial hemorrhage. Hemodynamics, wall remodeling, and wall …
Smooth muscle cells and the formation, degeneration, and rupture of saccular intracranial aneurysm wall—a review of current pathophysiological knowledge
J Frösen - Translational stroke research, 2014 - Springer
Subarachnoid hemorrhage or intracerebral hemorrhage caused by rupture of a saccular
intracranial aneurysm (sIA) is often fatal and causes significant loss of productive live years …
intracranial aneurysm (sIA) is often fatal and causes significant loss of productive live years …
Upregulated signaling pathways in ruptured human saccular intracranial aneurysm wall: an emerging regulative role of Toll-like receptor signaling and nuclear factor …
BACKGROUND: Aneurysmal subarachnoid hemorrhage, almost always from saccular
intracranial aneurysm (sIA), is a devastating form of stroke that affects the working-age …
intracranial aneurysm (sIA), is a devastating form of stroke that affects the working-age …