Dose comparison study of allogeneic mesenchymal stem cells in patients with ischemic cardiomyopathy (the TRIDENT study)
V Florea, AC Rieger, DL DiFede… - Circulation …, 2017 - Am Heart Assoc
Rationale: Cell dose and concentration play crucial roles in phenotypic responses to cell-
based therapy for heart failure. Objective: To compare the safety and efficacy of 2 doses of …
based therapy for heart failure. Objective: To compare the safety and efficacy of 2 doses of …
Transradial access in acute ischemic stroke intervention
DC Haussen, RG Nogueira, KG DeSousa… - Journal of …, 2016 - jnis.bmj.com
Objective To describe the feasibility and safety of transradial access (TRA) in the
interventional management of acute ischemic stroke (AIS). Methods A retrospective review …
interventional management of acute ischemic stroke (AIS). Methods A retrospective review …
Intramyocardial cell-based therapy with Lomecel-B during bidirectional cavopulmonary anastomosis for hypoplastic left heart syndrome: the ELPIS phase I trial
S Kaushal, JM Hare, JR Hoffman… - … Heart Journal Open, 2023 - academic.oup.com
Aims Hypoplastic left heart syndrome (HLHS) survival relies on surgical reconstruction of the
right ventricle (RV) to provide systemic circulation. This substantially increases the RV load …
right ventricle (RV) to provide systemic circulation. This substantially increases the RV load …
Unique Aspects of the Design of Phase I/II Clinical Trials of Stem Cell Therapy
IH Schulman, W Balkan, R Saltzman… - The Management of …, 2018 - books.google.com
This chapter will review the unique aspects and limitations of the design of phase I/II (safety
and efficacy) clinical trials of stem cell therapy. Although the classical pharmacologic …
and efficacy) clinical trials of stem cell therapy. Although the classical pharmacologic …
Intramyocardial cell-based therapy during bidirectional cavopulmonary anastomosis for hypoplastic left heart syndrome: The ELPIS phase I trial
Background Hypoplastic left heart syndrome (HLHS) survival relies on surgical
reconstruction for the right ventricle (RV) to provide systemic circulation. This leads to …
reconstruction for the right ventricle (RV) to provide systemic circulation. This leads to …
Abstract T MP5: Factors Determining Consent in a Randomized Trial of Intra-Arterial Stem Cell Therapy for Sub-Acute Ischemic Stroke
RN Pafford, DC Haussen, KN Ramdas, D McBee… - Stroke, 2015 - Am Heart Assoc
Background: Obtaining consent from eligible patients in randomized stroke trials can be
challenging. Stem cells are controversial in general and may add further hurdles to consent …
challenging. Stem cells are controversial in general and may add further hurdles to consent …
Long-Term Transplant-Free Survival is Improved in Hypoplastic Left Heart Syndrome With Cell-Based Therapy
S Kaushal, E Naioti, KN Ramdas, D Mehranfard… - Circulation, 2023 - Am Heart Assoc
Hypoplastic left heart syndrome (HLHS) is a univentricular congenital heart defect that has
high morbidity and mortality and requires three-stage surgical reconstruction so that the right …
high morbidity and mortality and requires three-stage surgical reconstruction so that the right …
The Effects of Multiple Doses of Lomecel‐B, Longeveron's Cell‐based Therapy, on Alzheimer's disease: Study Design and Rationale of this Phase 2a Multi‐center …
KN Ramdas, M Brody, B Herskowitz… - Alzheimer's & …, 2022 - Wiley Online Library
Background Lomecel‐B is an allogeneic medicinal signaling cell (MSC) formulation under
clinical investigation for Alzheimer's disease (AD). We have successfully completed a …
clinical investigation for Alzheimer's disease (AD). We have successfully completed a …
Abstract WP145: Intra-arterial Stem Cell Therapy for a Persistent Vegetative State Patient: A DTI Analysis of Recovery
KN Ramdas, L Guada, R Pafford, D Haussen… - Stroke, 2016 - Am Heart Assoc
Background: Cell therapy is promising in pre-clinical studies of global ischemia. The aim of
this pilot study is to describe the first intra-arterial (IA) delivery of bone marrow derived ALD …
this pilot study is to describe the first intra-arterial (IA) delivery of bone marrow derived ALD …