Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

M Goyal, BK Menon, WH Van Zwam, DWJ Dippel… - The Lancet, 2016 - thelancet.com
Background In 2015, five randomised trials showed efficacy of endovascular thrombectomy
over standard medical care in patients with acute ischaemic stroke caused by occlusion of …

[HTML][HTML] Thrombectomy within 8 hours after symptom onset in ischemic stroke

TG Jovin, A Chamorro, E Cobo… - … England Journal of …, 2015 - Mass Medical Soc
Background We aimed to assess the safety and efficacy of thrombectomy for the treatment of
stroke in a trial embedded within a population-based stroke reperfusion registry. Methods …

Design and validation of a prehospital stroke scale to predict large arterial occlusion: the rapid arterial occlusion evaluation scale

N Pérez de la Ossa, D Carrera, M Gorchs, M Querol… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—We aimed to develop and validate a simple prehospital stroke
scale to predict the presence of large vessel occlusion (LVO) in patients with acute stroke …

Effect of bypassing the closest stroke center in patients with intracerebral hemorrhage: a secondary analysis of the RACECAT randomized clinical trial

A Ramos-Pachón, D Rodríguez-Luna… - JAMA …, 2023 - jamanetwork.com
Importance Prehospital transfer protocols are based on rapid access to reperfusion
therapies for patients with ischemic stroke. The effect of different protocols among patients …

Reperfusion therapies for acute ischemic stroke: an update

L Dorado, M Millán, A Dávalos - Current cardiology reviews, 2014 - ingentaconnect.com
Acute ischemic stroke is a major cause of morbidity and mortality in developed countries.
Intravenous thrombolysis with tissue plasminogen activator (tPA) within 4.5 hours of …

[HTML][HTML] Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent …

N DeGregorio-Rocasolano, O Martí-Sistac, J Ponce… - Redox biology, 2018 - Elsevier
Despite transferrin being the main circulating carrier of iron in body fluids, and iron overload
conditions being known to worsen stroke outcome through reactive oxygen species (ROS) …

[HTML][HTML] Targeting pro-oxidant iron with deferoxamine as a treatment for ischemic stroke: safety and optimal dose selection in a randomized clinical trial

M Millán, N DeGregorio-Rocasolano… - Antioxidants, 2021 - mdpi.com
A role of iron as a target to prevent stroke-induced neurodegeneration has been recently
revisited due to new evidence showing that ferroptosis inhibitors are protective in …

Revalidation of the RACE scale after its regional implementation in Catalonia: a triage tool for large vessel occlusion

D Carrera, M Gorchs, M Querol, S Abilleira… - Journal of …, 2019 - jnis.bmj.com
Background and purpose Our aim was to revalidate the RACE scale, a prehospital tool that
aims to identify patients with large vessel occlusion (LVO), after its region-wide …

D-dimer as predictor of large vessel occlusion in acute ischemic stroke

A Ramos-Pachón, E López-Cancio, A Bustamante… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Improving prehospital triage of large vessel occlusion (LVO)
would reduce time to reperfusion therapies. We aimed to study early predictors of LVO in …

Predictive value of modifications of the prehospital rapid arterial occlusion evaluation scale for large vessel occlusion in patients with acute stroke

D Carrera, BCV Campbell, J Cortés, M Gorchs… - Journal of Stroke and …, 2017 - Elsevier
Background Prehospital clinical scales to identify patients with acute stroke with a large
vessel occlusion (LVO) and direct them to an endovascular-capable stroke center are …