Intravenous infusion of mesenchymal stem cells promotes functional recovery in a model of chronic spinal cord injury

T Morita, M Sasaki, Y Kataoka-Sasaki, M Nakazaki… - Neuroscience, 2016 - Elsevier
Intravenous infusion of mesenchymal stem cells (MSCs) derived from adult bone marrow
improves behavioral function in rat models of spinal cord injury (SCI). However, most studies …

Small extracellular vesicles released by infused mesenchymal stromal cells target M2 macrophages and promote TGF‐β upregulation, microvascular stabilization and …

M Nakazaki, T Morita, KL Lankford… - Journal of …, 2021 - Wiley Online Library
Intravenous (IV) infusion of bone marrow‐derived mesenchymal stem/stromal cells (MSCs)
stabilizes the blood‐spinal cord barrier (BSCB) and improves functional recovery in …

[HTML][HTML] Intravenous infusion of auto serum-expanded autologous mesenchymal stem cells in spinal cord injury patients: 13 case series

O Honmou, T Yamashita, T Morita, T Oshigiri… - Clinical Neurology and …, 2021 - Elsevier
Background Although spinal cord injury (SCI) is a major cause of disability, current
therapeutic options remain limited. Recent progress in cellular therapy with mesenchymal …

Synergic effects of rehabilitation and intravenous infusion of mesenchymal stem cells after stroke in rats

Y Sasaki, M Sasaki, Y Kataoka-Sasaki… - Physical …, 2016 - academic.oup.com
Background Intravenous infusion of mesenchymal stem cells (MSCs) derived from adult
bone marrow improves behavioral function in rat stroke models. Rehabilitation therapy …

Intravenous infusion of mesenchymal stem cells improves impaired cognitive function in a cerebral small vessel disease model

M Nakazaki, M Sasaki, Y Kataoka-Sasaki, S Oka… - Neuroscience, 2019 - Elsevier
Cerebral small vessel disease (CSVD) is not only a cause of vascular dementia (VD) but
also a contributing factor to Alzheimer's disease (AD). The essential pathological feature of …

Intravenous infusion of mesenchymal stem cells inhibits intracranial hemorrhage after recombinant tissue plasminogen activator therapy for transient middle cerebral …

M Nakazaki, M Sasaki, Y Kataoka-Sasaki, S Oka… - Journal of …, 2017 - thejns.org
OBJECTIVE Reperfusion therapy with intravenous recombinant tissue plasminogen
activator (rtPA) is the standard of care for acute ischemic stroke. However, hemorrhagic …

Predictors of hyperperfusion syndrome before and immediately after carotid artery stenting in single-photon emission computed tomography and transcranial color …

T Iwata, T Mori, H Tajiri, M Nakazaki - Neurosurgery, 2011 - journals.lww.com
BACKGROUND: Hyperperfusion syndrome (HPS) is a critical complication after carotid
artery stenting (CAS) and carotid endarterectomy (CEA). OBJECTIVE: To identify predictors …

Preservation of interhemispheric cortical connections through corpus callosum following intravenous infusion of mesenchymal stem cells in a rat model of cerebral …

H Nagahama, M Nakazaki, M Sasaki… - Brain research, 2018 - Elsevier
Systemic administration of mesenchymal stem cells (MSCs) following cerebral infarction
exerts functional improvements. Previous research has suggested potential therapeutic …

Intravenous infusion of mesenchymal stem cells alters motor cortex gene expression in a rat model of acute spinal cord injury

T Oshigiri, T Sasaki, M Sasaki… - Journal of …, 2019 - liebertpub.com
Recent evidence has demonstrated that remote responses in the brain, as well as local
responses in the injured spinal cord, can be induced after spinal cord injury (SCI) …

Intravenous infusion of mesenchymal stem cells promotes functional recovery in a rat model of chronic cerebral infarction

T Namioka, A Namioka, M Sasaki… - Journal of …, 2018 - thejns.org
OBJECTIVE Intravenous infusion of mesenchymal stem cells (MSCs) derived from adult
bone marrow improves behavioral function in rat models of cerebral infarction. Although …