Innovations in interventional cardiology historically predate those in neuro-intervention. As
such, studying trends in interventional cardiology can be useful in exploring avenues to …

There is no treatment for people with spinal cord injury that leads to significant functional
improvements. The extracellular matrix is an intricate, 3-dimensional, structural framework …

An injury to the spinal cord causes long-lasting loss of nervous tissue because endogenous
nervous tissue repair and regeneration at the site of injury is limited. We engineered an …

Hepatic stellate cells (HSCs) drive hepatic fibrosis. Therapies that inactivate HSCs have
clinical potential as antifibrotic agents. We previously identified acid ceramidase (aCDase) …

Rationale α v integrins, key regulators of transforming growth factor-β activation and
fibrogenesis in in vivo models of pulmonary fibrosis, are expressed on abnormal epithelial …

Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults, and
despite optimized treatment options, median survival remains dismal. Contemporary …

A bone marrow-derived mesenchymal stromal cell (MSC) transplant and a bioengineered
nanofiber-hydrogel composite (NHC) have been shown to stimulate nervous tissue repair in …

Resistance mechanisms employed by high-grade gliomas allow them to successfully evade
current standard treatment of chemotherapy and radiation treatment. Withaferin A (WA) …

Rationale: αv integrins, key regulators of transforming growth factor‑β activation and
fibrogenesis in in vivo models of pulmonary fibrosis, are expressed on abnormal epithelial …