Diagnostic methods and treatment options for focal cortical dysplasia

R Guerrini, M Duchowny, P Jayakar, P Krsek… - …, 2015 - Wiley Online Library
Our inability to adequately treat many patients with refractory epilepsy caused by focal
cortical dysplasia (FCD), surgical inaccessibility and failures are significant clinical …

The present and the future of neuroimaging in amyotrophic lateral sclerosis

F Agosta, A Chiò, M Cosottini… - American journal …, 2010 - Am Soc Neuroradiology
In patients with ALS, conventional MR imaging is frequently noninformative, and its use has
been restricted to excluding other conditions that can mimic ALS. Conversely, the extensive …

[HTML][HTML] Bevacizumab for the treatment of radiation-induced cerebral necrosis: a systematic review of the literature

D Delishaj, S Ursino, F Pasqualetti… - Journal of clinical …, 2017 - ncbi.nlm.nih.gov
Radiation necrosis (RN) of brain tissue is a serious late complication of brain irradiation and
recently bevacizumab has been suggested as treatment option of RN. There is a lack of data …

[HTML][HTML] Hypophysitis secondary to cytotoxic T-lymphocyte–associated protein 4 blockade: insights into pathogenesis from an autopsy series

P Caturegli, G Di Dalmazi, M Lombardi… - The American journal of …, 2016 - Elsevier
Hypophysitis that develops in cancer patients treated with monoclonal antibodies blocking
cytotoxic T-lymphocyte–associated protein 4 (CTLA-4; an inhibitory molecule classically …

MR imaging of the substantia nigra at 7 T enables diagnosis of Parkinson disease

M Cosottini, D Frosini, I Pesaresi, M Costagli, L Biagi… - Radiology, 2014 - pubs.rsna.org
Purpose To evaluate the anatomy of the substantia nigra (SN) in healthy subjects by
performing 7-T magnetic resonance (MR) imaging of the SN, and to prospectively define the …

7T MRI in focal epilepsy with unrevealing conventional field strength imaging

A De Ciantis, C Barba, L Tassi, M Cosottini… - …, 2016 - Wiley Online Library
Objective To assess the diagnostic yield of 7T magnetic resonance imaging (MRI) in
detecting and characterizing structural lesions in patients with intractable focal epilepsy and …

Diffusion-Tensor MR Imaging of Corticospinal Tract in Amyotrophic Lateral Sclerosis and Progressive Muscular Atrophy1

M Cosottini, M Giannelli, G Siciliano, G Lazzarotti… - Radiology, 2005 - pubs.rsna.org
PURPOSE: To prospectively evaluate several diffusion-tensor magnetic resonance (MR)
imaging indexes (mean diffusivity [MD], fractional anisotropy [FA], and eigenvalues) of …

[HTML][HTML] Cerebello-thalamo-cortical network is intrinsically altered in essential tremor: evidence from a resting state functional MRI study

V Nicoletti, P Cecchi, I Pesaresi, D Frosini… - Scientific reports, 2020 - nature.com
Cerebello-thalamo-cortical network is suggested to be involved in the pathophysiology of
Essential Tremor (ET). 23 patients with ET and 23 matched HC underwent a 3T-MRI with …

Brainstem neurodegeneration correlates with clinical dysfunction in SCA1 but not in SCA2. A quantitative volumetric, diffusion and proton spectroscopy MR study

L Guerrini, F Lolli, A Ginestroni, G Belli, RD Nave… - Brain, 2004 - academic.oup.com
Magnetic resonance (MR) techniques enable in vivo measurement of the atrophy of the
brainstem and cerebellum in spinocerebellar ataxia type 1 (SCA1) and 2 (SCA2) patients …

Multi-site repeatability and reproducibility of MR fingerprinting of the healthy brain at 1.5 and 3.0 T

G Buonincontri, L Biagi, A Retico, P Cecchi, M Cosottini… - Neuroimage, 2019 - Elsevier
Fully-quantitative MR imaging methods are useful for longitudinal characterization of
disease and assessment of treatment efficacy. However, current quantitative MRI protocols …