Objective We developed a method for fabricating a three-dimensional hollow and elastic
aneurysm model useful for surgical simulation and surgical training. In this article, we …

To facilitate clinical trials of disease-modifying therapies for Alzheimer's disease, which are
expected to be most efficacious at the earliest and mildest stages of the disease,, supportive …

Humoral responses in coronavirus disease 2019 (COVID-19) are often of limited durability,
as seen with other human coronavirus epidemics. To address the underlying etiology, we …

Wee1 is a tyrosine kinase that phosphorylates and inactivates CDC2 and is involved in G2
checkpoint signaling. Because p53 is a key regulator in the G1 checkpoint, p53-deficient …

Alzheimer's disease (AD) is the most common and devastating dementia. Simple and
practical biomarkers for AD are urgently required for accurate diagnosis and to facilitate the …

Fuji Micra Inc. has recently achieved success in a challenging and prospective project that
produces the smallest pig in the world, the “Microminipig”, at a breeding farm at the foothills …

Advances in the understanding of the molecular basis for acute myeloid leukemia (AML)
have generated new potential targets for treatment. Fms-like tyrosine kinase 3 (FLT3) is one …

Abstract Background Carotid web (CaW) is non-atheromatous, shelf-like intraluminal
projection, generally affecting the posterolateral wall of the proximal internal carotid artery …

Systemic sclerosis (SSc) is an autoimmune fibrotic disease whose pathogenesis is poorly
understood and lacks effective therapies. We undertook quantitative analyses of T cell …

Tumor-associated macrophages (TAMs) promote tumor progression and inhibit anti-tumor
immune response by producing various mediators and preferentially express CD163 …