A long-standing goal of spinal cord injury research is to develop effective repair strategies,
which can restore motor and sensory functions to near-normal levels. Recent advances in …

Background The clinical practice of platelet-rich plasma (PRP) therapy has grown
significantly in recent years in multiple medical specialties. However, comparisons of PRP …

At the time of writing of this article, there have been over 110 million cases and 2.4 million
deaths worldwide since the start of the Coronavirus Disease 2019 (COVID-19) pandemic …

Multiple sclerosis (MS) is characterized by demyelination and progressive neurological
disability. Previous studies have reported defects to mitochondria in MS including decreased …

OBJECTIVE Frailty is a clinical state of increased vulnerability due to age-associated decline
and has been well established as a perioperative risk factor. Geriatric patients have a higher …

Background Recently, there has been increased interest in patient satisfaction measures
such as Press Ganey and Hospital Consumer Assessment of Healthcare Providers and …

Although hypothermia has shown to protect against ischemic and traumatic neuronal death,
its potential role in neurologic recovery following traumatic spinal cord injury (TSCI) remains …

OBJECTIVE Tranexamic acid (TXA) is an antifibrinolytic agent associated with reduced
blood loss and mortality in a wide range of procedures, including spine surgery, traumatic …

Despite the peripheral nervous systems (PNS) capacity to regenerate, functional restoration
is highly variable following peripheral nerve injury (PNI), oftentimes leading to persistent …

Background Incidental or intentional durotomy in spine surgery is associated with a risk of
cerebrospinal fluid (CSF) leakage and reoperation. Several strategies have been …